58583-90-7Relevant articles and documents
DICATION COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF
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Paragraph 0041-0042, (2021/07/17)
A dication compound represented by formula (I), stereoisomers having the structure of formula (I) or a mixture of the stereoisomers, a pharmaceutically acceptable salt, a solvate, or a eutectic crystal, and a composition thereof, and use of a composition, are capable of producing neuromuscular junction retardation, formed of same with a pharmaceutically acceptable carrier in the field of preparation of a medicament for muscular flaccidity.
Cyano-containing biquaternary ammonium compound as well as preparation method and application thereof
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Paragraph 0098-0100, (2021/07/10)
The invention relates to a cyano-containing biquaternary ammonium compound as well as a preparation method and application thereof, and particularly discloses a biquaternary ammonium compound as shown in a formula (I), or a crystal form, a solvate, a stereoisomer, an isotope substitute or a salt thereof. The biquaternary ammonium compound does not contain nitro, so that the potential safety hazard of nitro-containing compounds is effectively avoided; meanwhile, the biquaternary ammonium compound is low in single-time medication dosage and quick in effect taking, can provide a thorough muscle relaxation effect for 2-10 minutes, can realize a super-short-acting non-depolarization muscle relaxation effect only by depending on metabolism of an organism, and quickly and automatically fades after playing the super-short-acting muscle relaxation effect. Therefore, the biquaternary ammonium compound, or the crystal form thereof, or the solvate thereof, or the stereoisomer thereof, or the isotope substitute thereof, or the salt thereof provided by the invention has a very good application prospect in preparation of skeletal muscle relaxation drugs with low dosage, quick effect, quick recovery and small toxic and side effects.
A formal method for the de-N,N-dialkylation of Sommelet-Hauser rearrangement products
Tayama, Eiji,Sato, Ryota,Takedachi, Keisuke,Iwamoto, Hajime,Hasegawa, Eietsu
experimental part, p. 4710 - 4718 (2012/07/28)
Selective amine de-alkylation enables the conversion of Sommelet-Hauser rearrangement products into 2-aryl-2-bromoacetic acid derivatives. These compounds are valuable synthetic intermediates in the synthesis of α-aryl-α-amino or α-aryl-β-amino acid deriv
POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS
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, (2010/04/23)
A positive resist composition comprises (A) a resin component which becomes soluble in an alkaline developer under the action of an acid and (B) an acid generator. The resin (A) is a polymer comprising recurring units containing a non-leaving hydroxyl group represented by formula (1) wherein R1 is H, methyl or trifluoromethyl, X is a single bond or methylene, m is 1 or 2, and the hydroxyl group attaches to a secondary carbon atom. The composition is improved in resolution when processed by lithography.
Reaction of methyl diazoacetate with amines catalyzed by Ru 2(OAc)4Cl
Maidanova,Bakeeva,Sultanova,Biglova,Dokichev
experimental part, p. 1461 - 1465 (2011/03/17)
Reactions of primary and secondary amines with methyl diazoacetate in the presence of Ru2(OAc)4Cl gave the corresponding N-substituted glycine methyl esters in almost quantitative yield. Catalytic decomposition of methyl diazoacetate
Novel tertiary (meth)acrylates having lactone structure, polymers, resist compositions and patterning process
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, (2008/06/13)
Novel tertiary (meth)acrylate compounds having a lactone structure are polymerizable into polymers having improved transparency, especially at the exposure wavelength of an excimer laser and dry etching resistance. Resist compositions comprising the polymers are sensitive to high-energy radiation, have a high resolution, and lend themselves to micropatterning with electron beams or deep-UV rays.
