58633-04-8

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-Amino-3,5-dibromobenzonitrile is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides due to its unique chemical structure and reactivity.
Used in Dyes and Pigments Production:
4-Amino-3,5-dibromobenzonitrile is utilized as an intermediate in the production of dyes and pigments, playing a crucial role in the coloration processes of various materials and products.
Used in Chemical Research and Development:
4-Amino-3,5-dibromobenzonitrile is employed in research and development settings within the chemical and pharmaceutical industries, where it aids in the exploration of new chemical reactions and the creation of novel compounds for various applications.
Used in Laboratory Synthesis:
4-Amino-3,5-dibromobenzonitrile is used in laboratory synthesis processes, where it is produced through a simple reaction between 3,5-dibromobenzonitrile and ammonia, serving as a model compound for understanding chemical behavior and reaction mechanisms.

InChI:InChI=1/C7H4Br2N2/c8-5-1-4(3-10)2-6(9)7(5)11/h1-2H,11H2

Upstream product

• 873-74-5 4-Aminobenzonitrile 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 54381-73-6 C₇H₃Br₂N₃O₂ 
• 105170-52-3 3,5-dibromo-4-iodobenzonitrile 
• 1155287-11-8 (2,6-dibromo-4-cyano-phenyl)-thiourea 
• 97165-77-0 3,5-dibromobenzonitrile 
• 1261225-77-7 4-amino-3,5-dicyclopropylbenzonitrile 
• 107828-98-8 N-[2-(2,6-Dicyano-4-nitro-phenylazo)-5-dipropylamino-phenyl]-benzamide 
• 107829-04-9 N-[5-Diethylamino-2-(2,4,6-tricyano-phenylazo)-phenyl]-acetamide 
• 203051-50-7 2'-(3,5-Dichloro-phenylsulfanylamino)-[1,1';3',1'']terphenyl-5'-carbonitrile 
• 98278-79-6 2,6-Dibrom-4-cyano-nitrosobenzol 

Relevant academic research and scientific papers

SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS

Described herein are compounds of Formula (I), Formula (I-A), and Formula (I-B), solvates thereof, tautomers thereof, and pharmaceutically acceptable salts of the foregoing, Further described herein are methods of inhibiting NLRP3 using said compounds, and methods of and compositions useful in treating NLRP3-dependent disorders.

DIPHENYLUREA COMPOUND DERIVATIVE

To provide a novel diphenylurea compound derivative that is involved in the functional regulation of an ion transporter of a plant.SOLUTION: The present invention relates to a diphenylurea compound derivative represented by the following formula (1) (each

1,1,2,2-Tetrahydroperoxy-1,2-Diphenylethane: An efficient and high oxygen content oxidant in various oxidative reactions

Several oxidative approaches namely thiocyanation of aromatic compounds, epoxidation of alkenes, amidation of aromatic aldehydes, epoxidation of α β-unsaturated ketones, oxidation of sulfides to sulfoxides and sulfones, bayer-villeger reaction, bromination and iodation of aniline and phenol derivatives oxidative esterification, oxidation of pyridines and oxidation of secondary, allylic and benzyllic alcohols were carried out using 1,1,2,2-Tetrahydroperoxy-1,2-Diphenylethane as the potential solid oxidant which can be stored for several months without any loss in its activity. All of the procedures were accomplished via mild reaction conditions and the products were afforded in high yields and short reaction times.

Green process development for the preparation of 2,6-dibromo-4-nitroaniline from 4-nitroaniline using bromide-bromate salts in an aqueous acidic medium

An organic solvent-free process for the preparation of 2,6-dibromo-4-nitroaniline, (an important intermediate in the synthesis of azo disperse dyes) from 4-nitroaniline using 2:1 bromide-bromate salts under an aqueous acidic medium at ambient conditions has been developed. The 2:1 bromide-bromate couple could be obtained by mixing pure NaBr/NaBrO3 salts or by adjusting the 5:1 mole ratio of NaBr/NaBrO3 (obtained in an aqueous solution as an intermediate from the bromine manufacture industry by a cold process) to 2:1 by the addition of a suitable oxidant. After completion of the reaction the product was purified by simple filtration and washing with water. The aqueous acidic filtrate was recycled up to five times without loss of purity and yield of the product. The method was extended to other aromatic substrates.

Fast and efficient bromination of aromatic compounds with ammonium bromide and Oxone

A highly efficient, rapid and regioselective protocol was developed for the ring bromination of aromatic compounds under mild conditions with ammonium bromide as a source of bromine source and Oxone (potassium peroxysulfate) as an oxidant. No metal catalyst or acidic additive is required. A variety of aromatic compounds, including methoxy, hydroxy, amino, and alkyl arenes, reacted smoothly to give the corresponding monobrominated products in good to excellent yields in very short reaction times. Moreover, dibromination of deactivated anilines to give the corresponding dibromides proceeded in high yields. Interestingly, 1-(2-naphthyl)ethanone provided a ring-brominated product. Georg Thieme Verlag Stuttgart . New York.

Stable Thioaminyl Radicals Having Functional Groups: Generation, ESR Spectra, Isolation, X-ray Crystallographic Analyses, and Magnetic Characterization of N-(Arylthio)-4-(ethoxycarbonyl)-2,6-diarylphenylaminyls, N-(Arylthio)-4-acetyl-2,6-diarylphenylaminyls, and N-(Arylthio)-4-cyano-2,6-diarylphenylaminyls

Oxidation of N-(arylthio)-4-(ethoxycarbonyl)-2,6-diarylanilines (9), N-(arylthio)-4-acetyl-2,6-diarylanilines (10), and N-(arylthio)-4-cyano-2,6-diarylanilines (11) with PbO2 yielded quite persistent N-(arylthio)-4-(ethoxycarbonyl)-2,6-diarylphenylaminyls(4), N-(arylthio)-4-acetyl-2,6-diarylphenylaminyls (5), and N-(arylthio)-4-cyano-2,6-diarylphenylaminyls (6), respectively, and they were isolated as pure radical crystals. On the other hand, N-(arylthio)-4-nitro-2,6-diarylphenylaminyls (6), and N-(arylthio)-4-chloro-2,6-diarylphenylaminyls (7), were unstable and soon decomposed. The X-ray crystallographic analyses of N-[(2,4-dichlorophenyl)thio]-4-acetyl-2,6-diphenylphenylaminyl (5c) and N-[(2,4-dichlorophenyl)thio]-4-cyano-2,6-diphenylphenylaminyl (6c) showed that the Ph-N-S-Ph π-framework is planar, and the 2- and 6-phenyl groups are twisted from the coplane. The ESR studies for 4-8 showed that their hyperfine coupling constants are nearly identical to each other and that the unpaired electron is extensively delocalized onto the anilino benzene ring and the arylthiyl group. The magnetic susceptibility measurements were carried out for five thioaminyl radical crystals and showed that one radical couples ferromagnetically with 2J/kB = 16.0 K, and the other four radicals couple antiferromagnetically with 2J/kB = -15.6 to -194.6 K or θ = -0.6 to -5.0 K.

3-aryl of heteroaryl-7-heteroaralkylamido cephalosporin compounds, compositions and methods of use

A compound of the formula I is disclosed. STR1 R13 represents hydrogen, NH2, C1-4 alkyl, C1-4 alkylamino or di(C1-4) alkylamino-; Y represents CH or N; Y" represents (a) CRy' Rz' with Ry' and Rz'

Synthesis and Spectral Characterization of Blue Dyes of the Benzene Series

53 Donor-acceptor substituted azo dyes of the benzene series were prepared by diazonium-coupling reactions (1a-s) or halogen-cyanide exchange (->2a-x, 3a-j).Described are the preparation of the amines 4a-m and the coupling compounds 5a-t and the procedure of diazotizing and coupling.The colouristic and spectroscopic data show that compounds of the general formula 1 are excellent brilliant blue azo dyes usefull for dyeing polyester material.