58646-00-7

Usage

Uses

Used in Organic Synthesis:
(E)-N-(3-bromobenzylidene)propan-1-amine is utilized as a reagent in organic synthesis, where its unique structure and functional groups enable the creation of a wide range of chemical products. Its benzylidene and bromo substituents facilitate various chemical reactions, making it a valuable building block for the development of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-N-(3-bromobenzylidene)propan-1-amine serves as an intermediate in the development of new drugs. Its chiral center and the potential for different stereoisomeric forms allow for the exploration of various biological activities. (E)-N-(3-broMobenzylidene)propan-1-aMine's structure and properties make it a promising candidate for the creation of novel therapeutic agents.
Used in Chemical Reactions:
(E)-N-(3-bromobenzylidene)propan-1-amine is also employed in chemical reactions due to its reactive functional groups. The benzylidene group can participate in various reactions, such as electrophilic aromatic substitution, while the bromo substituent can undergo nucleophilic substitution or elimination reactions. This versatility makes it a useful compound for constructing complex molecular structures and exploring new reaction pathways.

Upstream product

• 107-10-8 propylamine 
• 3132-99-8 m-bromobenzoic aldehyde 

Downstream Products

• 1262325-35-8 4-(3-bromobenzylidene)-2-methyl-1-propyl-1H-imidazol-5(4H)-one 
• 90389-92-7 N-(3-bromobenzyl)propylamine 

Relevant academic research and scientific papers

A latent reaction in a model GFP chromophore revealed upon confinement: Photohydroxylation of ortho -halo benzylidene-3-methylimidazolidiones via an electrocylization process

Excited state behavior of halogen substituted model GFP chromophores was investigated in an acetonitrile solution and in a confined environment provided by an octa acid capsule in water. Of the ortho, meta, and para halogen substituted GFP chromophores on

Preparation of benzolactams by Pd(OAC)2-catalyzed direct aromatic carbonylation

We developed a new method for Pd(II)-catalyzed direct aromatic carbonylation in a phosphine-free catalytic system using Pd(OAc)2 and Cu(OAc)2 in an atmosphere of CO gas containing air. The carbonylation proceeded with ortho-palladation, inducing a remarkable site selectivity to afford a variety of five- or six-membered benzolactams from secondary ω-arylalkylamines, such as N-alkylbenzylamines or N-alkylphenethylamines. Copyright

Separation of Ring Polar and Resonance Effects on the Rate Constants for Uncatalyzed N-Arylidenepropylamine Formation in Methanol

Rate constants are reported for the reaction of a series of 19 ring-substituted benzaldehydes with propylamine in methanol and in O-d-methanol at different temperatures and of three of them with 2-methoxyethylamine and 2,2-dimethoxyethylamine.The large di

Benzylamines: Synthesis and evaluation of antimycobacterial properties

The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.