90389-92-7

Usage

Uses

Used in Pharmaceutical Industry:
N-(3-bromobenzyl)-N-propylamine is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, N-(3-bromobenzyl)-N-propylamine is employed as a building block for the creation of complex organic molecules. Its presence in these molecules can influence their properties and reactivity, making it a valuable asset in organic synthesis.
Used in Chemical Synthesis as a Reagent:
N-(3-bromobenzyl)-N-propylamine is utilized as a reagent in chemical synthesis, particularly for the preparation of substituted amines. Its ability to participate in various chemical reactions makes it a useful tool for chemists in developing new compounds and materials.
Safety Considerations:
Due to its mild to moderate toxicity, N-(3-bromobenzyl)-N-propylamine should be handled with care. Proper safety procedures and guidelines must be followed to ensure the safety of individuals working with N-(3-bromobenzyl)-N-propylamine, minimizing potential health risks and environmental impact.

InChI:InChI=1/C10H14BrN/c1-2-6-12-8-9-4-3-5-10(11)7-9/h3-5,7,12H,2,6,8H2,1H3

Upstream product

• 58646-00-7 [1-(3-Bromo-phenyl)-meth-(E)-ylidene]-propyl-amine 
• 398150-56-6 tert-butyl (3-bromo-benzyl)propylcarbamate 

Downstream Products

• 398150-57-7 N-(3-bromo benzyl)-N-propylbenzamide 

Relevant academic research and scientific papers

Biaromatic compound activators of PPARy-type receptors

The invention relates to novel biaromatic compounds which correspond to the general formula (I) below: and also to the method for preparing them and their use in pharmaceutical compositions intended for use in human or veterinary medicine (in dermatology, and also in the field of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or alternatively in cosmetic compositions.

Preparation of benzolactams by Pd(OAC)2-catalyzed direct aromatic carbonylation

We developed a new method for Pd(II)-catalyzed direct aromatic carbonylation in a phosphine-free catalytic system using Pd(OAc)2 and Cu(OAc)2 in an atmosphere of CO gas containing air. The carbonylation proceeded with ortho-palladation, inducing a remarkable site selectivity to afford a variety of five- or six-membered benzolactams from secondary ω-arylalkylamines, such as N-alkylbenzylamines or N-alkylphenethylamines. Copyright

Benzylamines: Synthesis and evaluation of antimycobacterial properties

The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.