58663-25-5Relevant academic research and scientific papers
Phenylalkylamines and salts thereof
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, (2008/06/13)
Compounds of the formula STR1 wherein R1 is hydrogen, --(CH2)n --R4 or --CO--R5, where n is 1 or 2, R4 is hydrogen, cyano or benzoyl, and R5 is hydrogen, lower alkoxy, benzyloxy, --CH2 --NH2, --CH(CH3)--NH2, --CH2 --NH--CH2 --C6 H5 or --CH(CH3)--NH--CH2 --C6 H5, R2 is hydrogen or methyl, and R3 is amino, nitro, --NH--CO--R6 or --NH--A--R7, where R6 is hydrogen, methyl, methoxy, ethoxy, methylthio or ethylthio, R7 is amino, methylamino or dimethylamino, and A is --CO-- or --SO2 --, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as hypertensives.
