58677-34-2

Basic information

• Product Name: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid
• Synonyms: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(SALTDATA: FREE)
• CAS NO: 58677-34-2
• Molecular Formula: C₄H₄N₂O₃
• Molecular Weight: 128.09
• Mol File: 58677-34-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 74 °C
• Boiling Point: 286.5°C at 760 mmHg
• Flash Point: 127.1°C
• Appearance: /
• Density: 1.464g/cm³
• Vapor Pressure: 0.00123mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: 2-8°C
• PKA: 2.34±0.32(Predicted)
• CAS DataBase Reference: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(58677-34-2)
• EPA Substance Registry System: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(58677-34-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 58677-34-2(Hazardous Substances Data)

Usage

Uses

4-?Methyl-?1,?2,?5-?oxadiazole-?3-?carboxylic Acid is a reactant in the preparation of a novel glycogen synthase kinase-?3β Inhibitor which may be used in the treatment of bipolar disorder, treating mania and depression.

InChI:InChI=1/C4H4N2O3/c1-2-3(4(7)8)6-9-5-2/h1H3,(H,7,8)

Upstream product

• 17647-69-7 3-ethyl-4-methyl-furazan 
• 165067-10-7 3-acetyl-4-methylfurazan 
• 4975-21-7 3,4-dimethylfurazan 

Downstream Products

• 53101-48-7 1-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-ethanone oxime 
• 53174-05-3 1-(4,5-diphenyl-4,5-dihydro-isoxazol-3-yl)-ethanone oxime 
• 37880-10-7 1-(5-phenyl-isoxazol-3-yl)-ethanone oxime 
• 78441-74-4 3-(hydroxymethyl)-4-methyl-1,2,5-oxadiazole 
• 1203662-05-8 N-[1-(4-tert-butylphenyl)-1H-indazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203662-06-9 N-[1-(3,5-dimethylphenyl)-1H-indazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203661-75-9 N-[1-(3-trifluoromethylphenyl)-1H-4,5,6,7-tetrahydroindazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203661-76-0 N-[1-(2-trifluoromethylphenyl)-1H-4,5,6,7-tetrahydroindazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203661-78-2 N-[1-(4-nitrophenyl)-1H-4,5,6,7-tetrahydroindazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203661-79-3 N-[1-(4-methoxylphenyl)-1H-4,5,6,7-tetrahydroindazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203661-80-6 N-[1-(4-fluorophenyl)-1H-4,5,6,7-tetrahydroindazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203661-81-7 N-[1-(4-bromophenyl)-1H-4,5,6,7-tetrahydroindazol-4-yl]-4-methylfurazan-3-carboxamide 
• 1203661-86-2 N-{1-[4-(4-methylfurazan-3-carbonylamino)phenyl]-1H-4,5,6,7-tetrahydroindazol-4-yl}-4-methylfurazan-3-carboxamide 
• 1203661-87-3 N-[1-(4-tert-butylphenyl)-1H-4,5,6,7-tetrahydrobenzotriazol-4-yl]-4-methylfurazan-3-carboxamide 

Relevant articles and documents

4-[(4-(CARBOXYETHYL) PIPERIDINYL) METHYL] PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

3-Substituted pyrrolidines having a 4-carboxypiperidinylmethyl substituent on the 4-position of the ring are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.