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4-methyl-1,2,5-oxadiazole-3-carboxylic acid is an organic compound characterized by its unique oxadiazole ring structure and a carboxylic acid functional group. It is known for its potential applications in various industries, particularly in the pharmaceutical sector, due to its chemical properties and reactivity.

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  • 58677-34-2 Structure
  • Basic information

    1. Product Name: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid
    2. Synonyms: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(SALTDATA: FREE)
    3. CAS NO:58677-34-2
    4. Molecular Formula: C4H4N2O3
    5. Molecular Weight: 128.09
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 58677-34-2.mol
  • Chemical Properties

    1. Melting Point: 74 °C
    2. Boiling Point: 286.5°C at 760 mmHg
    3. Flash Point: 127.1°C
    4. Appearance: /
    5. Density: 1.464g/cm3
    6. Vapor Pressure: 0.00123mmHg at 25°C
    7. Refractive Index: 1.517
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 2.34±0.32(Predicted)
    11. CAS DataBase Reference: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(58677-34-2)
    13. EPA Substance Registry System: 4-methyl-1,2,5-oxadiazole-3-carboxylic acid(58677-34-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 58677-34-2(Hazardous Substances Data)

58677-34-2 Usage

Uses

Used in Pharmaceutical Industry:
4-methyl-1,2,5-oxadiazole-3-carboxylic acid is used as a reactant for the preparation of a novel glycogen synthase kinase-3β (GSK-3β) inhibitor. This inhibitor may be utilized in the treatment of bipolar disorder, specifically targeting the manic and depressive episodes associated with the condition. 4-methyl-1,2,5-oxadiazole-3-carboxylic acid's reactivity and structural properties make it a valuable component in the development of new therapeutic agents for mental health disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 58677-34-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,6,7 and 7 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 58677-34:
(7*5)+(6*8)+(5*6)+(4*7)+(3*7)+(2*3)+(1*4)=172
172 % 10 = 2
So 58677-34-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2O3/c1-2-3(4(7)8)6-9-5-2/h1H3,(H,7,8)

58677-34-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methyl-1,2,5-oxadiazole-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names methyl-furazancarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:58677-34-2 SDS

58677-34-2Relevant articles and documents

4-[(4-(CARBOXYETHYL) PIPERIDINYL) METHYL] PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

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Page 33; 25, (2010/02/07)

3-Substituted pyrrolidines having a 4-carboxypiperidinylmethyl substituent on the 4-position of the ring are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.

4(SPIROPIPERIDINYL)METHYL SUBSTITUTED PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

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Page 42-43, (2010/02/07)

3-Substituted pyrrolidines having a spiropiperidinylmethyl substituent on the 4-position of the ring are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.

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