586972-32-9Relevant academic research and scientific papers
Traceable cancer cell photoablation with a new mitochondria-responsive and -activatable red-emissive photosensitizer
Yang, Chenlin,Hu, Rui,Lu, Fengxian,Guo, Xudong,Wang, Shuangqing,Zeng, Yi,Li, Yi,Yang, Guoqiang
, p. 3801 - 3804 (2019)
A mitochondria-responsive and -activatable photosensitizer (PS), MPS, composed of a pyridinium cation as a mitochondria targeting group and a dibenzylideneacetone derivative with environment-sensitive emission properties as the ROS generator and self-efficacy tracer, is reported. This multifunctional PS offers a new strategy for traceable photodynamic ablation of cancer cells.
NOVEL CURCUMIN DERIVATIVE
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Page/Page column 83, (2009/12/07)
The present invention provides a novel compound that is structurally similar to curcumin and has a suppressive effect on Aβ aggregation, a degradative effect on Aβ aggregates, an inhibitory effect on β-secretase, and a protective effect on neurons. The novel compound is a compound represented by the following general formula (Ia) or a salt thereof: wherein R1 represents a 4-hydroxy-3-methoxyphenyl group or the like, and R2 represents a 1H-indol-6-yl group or the like.
