58714-91-3Relevant academic research and scientific papers
GUANIDINE COMPOUNDS AND USE THEREOF
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Page/Page column 25; 48, (2015/11/09)
The present invention relates to guanidine compounds for inhibiting mitochondrial oxidative phosphorylation (OXPHOS) and use thereof. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating a OXPHOS-related disease, particularly cancer by inhibiting mitochondrial oxidative phosphorylation and reprogramming cellular metabolism.
Biguanide compounds and anti-diabetic compositions
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, (2008/06/13)
New biguanide compounds of the formula: STR1 wherein A is saturated or unsaturated cycloaliphatic hydrocarbyl, and the physiologically compatible salts thereof; display outstanding anti-diabetic effectiveness in the treatment of diabetes mellitus, without showing the typical side effects of biguanide treatment, viz., lactacidosis.
