58720-40-4

Upstream product

• 79-77-6 (E)-β-ionone 
• 36340-49-5 5,6-epoxy-trans-β-ionone 
• 54757-29-8 2-(Bromomethyl)-1,3,4-trimethylbenzene 
• 14583-98-3 1-tributylstannanyl-propan-2-one 
• 66248-70-2 4-(2,3,6-trimethyl-phenyl)-butan-2-ol 
• 105-45-3 acetoacetic acid methyl ester 
• 41381-36-6 2-bromo-1,3,4-trimethyl-benzene 
• 78-94-4 methyl vinyl ketone 
• 79644-41-0 2,3,6-trimethylphenyl trifluoromethanesulfonate 
• 488-23-3 1,2,3,4-Tetramethylbenzene 
• 30316-18-8 1,2-dihydro-3,5,8-trimethyl-naphthalene 
• 124211-42-3 4-(3,6-dimethyl-2-formylphenyl)butan-2-one 
• 124211-43-4 4-(2-Hydroxymethyl-3,6-dimethyl-phenyl)-butan-2-ol 
• 76964-13-1 2-formyl-3,4-dihydro-5,8-dimethylnaphthalene 

Downstream Products

• 59700-21-9 methyl-3 (trimethyl-2,3,6 phenyl)-5 pentene-1 ol-3 
• 124211-40-1 4-(2,3,6-trimethylphenyl)-3-bromobutan-2-one 
• 124211-41-2 5-(2,3,6-trimethylphenyl)-3-methylpenta-1,4-dien-3-ol 
• 57461-21-9 (3E)-4-(2,3,6-trimethylphenyl)but-3-en-2-one 
• 34341-29-2 2,3,6-trimethylbenzaldehyde 
• 2529-36-4 2,3,6-trimethylbenzoic acid 
• 476-73-3 1,2,3,4-benzenetetracaboxylic acid 

Relevant academic research and scientific papers

Selectivity in palladium catalyzed arylation: Synthetic application leading to aromatized ionone natural products

The selectivity in aromatic substitution vs conjugate addition during palladium catalyzed reactions has been controlled simply by changing the base. These reaction conditions have been applied to the syntheses of aromatized β-ionone natural products 1 and its dihydroderivatives 7.

A new synthesis of 4-(2,3,6-trimethylphenyl)butan-2-ol, a C13-norisoprenoid artifact from Vitis vinifera linn. and its conversion to several terpenic natural products of plant and marine origin

The four-step synthesis of 4-(2,3,6-trimethylphenyl)butan-2-ol (1), starts from 5,8-dimethyl-3,4-dihydro-2-naphthaldehyde (2).The trimethyldihydronaphthalene (10) obtained from the reduction of 2 is ozonised to the keto aldehyde (11), which is reduced to