58731-15-0Relevant academic research and scientific papers
Aromaheterocyclic derivatives as dopamine D4 receptor antagonists
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, (2008/06/13)
The present invention relates to an aromaheterocyclic derivative represented by formula [I]: wherein Z is a group represented by the following formula: wherein Ar1 is a phenyl group or a phenyl group substituted with a halogen atom or an alkyl group of 1 to 5 carbon atoms; Ar2 is a phenyl group optional substituted with substituents selected from the group consisting of a halogen atom, an alkyl group of 1 to 5 carbon atoms, an alkoxy group of 1 to 5 carbon atoms, a hydroxyl group and a trifluoromethyl group; B1-B2 is CH-CO or C=C(R1) wherein R1 is a hydrogen atom or an alkyl group of 1 to 5 carbon atoms; n is an integer of 1 to 4; or pharmaceutically acceptable salts thereof.
Arylpiperidine derivatives and use thereof
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Page column 11-12, (2010/11/30)
The present invention provides an arylpiperidine derivative of the formula (I) or a pharmaceutically acceptable salt thereof, which has antipsychotic effect: wherein D is a carbon atom or a nitrogen atom, E is a CH group or a nitrogen atom, G is an oxygen atom, a sulfur atom, a nitrogen atom or an NH group, Y1is a hydrogen atom or a halogen atom, n is an integer of 1 to 4, and R1is a group represented by any of the formulas (i) to (iv) defined in the specification.
Heteroaromatic derivatives
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, (2008/06/13)
An aromaheterocyclic derivative represented by the formula: wherein Z is a group represented by the following formula: wherein Ar1is a phenyl group or a phenyl group substituted with a halogen atom or an alkyl group of 1 to 5 carbon atoms, Rsu
