51037-74-2

Upstream product

• 3874-54-2 4-(4-fluorophenyl)-4-oxo-n-butyl chloride 

Downstream Products

• 58731-15-0 2-hydroxy-5-(2-chloroethyl)-4-(4-fluorophenyl)thiazole 
• 51037-40-2 1-(4-fluoro-phenyl)-2,4-di-morpholin-4-yl-butan-1-one 
• 204718-61-6 ethyl 5-(2-chloroethyl)-4-(4-fluorophenyl)-2-thiazolecarboxylate 
• 206436-62-6 2-methylthio-4-(2-chloroethyl)-5-(4-fluorophenyl)imidazole 
• 206436-62-6 2-methylthio-5-(2-chloroethyl)-4-(4-fluorophenyl)imidazole 
• 51037-56-0 1-(4-fluorophenyl)-2-hydroxy-4-<4-(2-oxo-1-benzimidazolinyl)-1-piperidyl>-1-butanone 
• 51037-51-5 1-(4-fluorophenyl)-2-hydroxy-4-<4-(2-methoxyphenyl)-1-piperazinyl>-1-butanone 
• 51037-58-2 1-(4-fluorophenyl)-2-hydroxy-4-<4-(2-pyridyl)-1-piperazinyl>-1-butanone 
• 51037-47-9 1-(4-fluorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone 

Relevant academic research and scientific papers

Arylpiperidine derivatives and use thereof

The present invention provides an arylpiperidine derivative of the formula (I) or a pharmaceutically acceptable salt thereof, which has antipsychotic effect: wherein D is a carbon atom or a nitrogen atom, E is a CH group or a nitrogen atom, G is an oxygen atom, a sulfur atom, a nitrogen atom or an NH group, Y1is a hydrogen atom or a halogen atom, n is an integer of 1 to 4, and R1is a group represented by any of the formulas (i) to (iv) defined in the specification.

Aromaheterocyclic derivatives as dopamine D4 receptor antagonists

The present invention relates to an aromaheterocyclic derivative represented by formula [I]: wherein Z is a group represented by the following formula: wherein Ar1 is a phenyl group or a phenyl group substituted with a halogen atom or an alkyl group of 1 to 5 carbon atoms; Ar2 is a phenyl group optional substituted with substituents selected from the group consisting of a halogen atom, an alkyl group of 1 to 5 carbon atoms, an alkoxy group of 1 to 5 carbon atoms, a hydroxyl group and a trifluoromethyl group; B1-B2 is CH-CO or C=C(R1) wherein R1 is a hydrogen atom or an alkyl group of 1 to 5 carbon atoms; n is an integer of 1 to 4; or pharmaceutically acceptable salts thereof.