5874-97-5 Usage
Chemical Properties
White or almost white, slightly hygroscopic, crystalline powder.
Uses
Different sources of media describe the Uses of 5874-97-5 differently. You can refer to the following data:
1. Beta2-adrenoceptor agonist; bronchodilator.
2. Bronchodilatator;Beta-adrenergic agonist
Brand name
Alupent (Boehringer Ingelheim); Prometa (Muro).
Therapeutic Function
Bronchodilator
Pharmacokinetics
Metaproterenol is a direct-acting resorcinol analogue of isoproterenol. The N-isopropyl is
β-directing, and the combination with the resorcinol ring system enhances the selectivity for the
β2-receptors. It is the least potent of the β2-selective agonists, however, most likely because of
the poor β2-selectivity of the isopropyl group. It has good oral bioavailability being resistant to
COMT and only slowly metabolized by MAO. When administered orally, it has an onset of
approximately 30 minutes with a 4-hour duration. Inhaled metaproterenol can have an onset as
quick as 5 minutes; however, it can be as long as 30 minutes in susceptible individuals.
Metaproterenol is available in tablet, syrup, and inhalation dosage forms and is recommended for
bronchial asthma attacks and treatment of acute asthmatic attacks in children 6 years of age and
older (5% solution for inhalation only). Metaproterenol has the same adverse effect profile as
other adrenergic agonists, but with a decreased incidence of arrhythmias.
Check Digit Verification of cas no
The CAS Registry Mumber 5874-97-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,7 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5874-97:
(6*5)+(5*8)+(4*7)+(3*4)+(2*9)+(1*7)=135
135 % 10 = 5
So 5874-97-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO3.H2O4S/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)
