58749-33-0

Usage

Uses

Used in Pharmaceutical Industry:
DIMETHYL 3-BROMOPHTHALATE is used as a key intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and medicines.
Used in Agrochemical Industry:
In the agrochemical sector, DIMETHYL 3-BROMOPHTHALATE is utilized as an intermediate for the production of agrochemicals, aiding in the creation of substances that protect crops and enhance agricultural productivity.
Used in Chemical Research:
DIMETHYL 3-BROMOPHTHALATE is employed as a research chemical, facilitating the exploration of new chemical reactions and the development of innovative organic synthesis methods.

Upstream product

• 116-69-8 3-bromophthalic acid 
• 74-88-4 methyl iodide 
• 34529-06-1 dimethyl 3-aminophthalate 

Downstream Products

• 1019854-30-8 dimethyl 3-[(trifluoromethylphenyl)amino]phthalate 
• 604-53-5 1,1'-bisnaphthalene 
• 861017-07-4 3-[1]naphthyl-phthalic acid 

Relevant academic research and scientific papers

SUBSTITUTED ISOINDOLINONES

Substituted isoindolinones of Formula (I), methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat or ameliorate diseases, disorders, or conditions associated with protein malfunction, such as cancer, are provided.

Conception of myeloperoxidase inhibitors derived from flufenamic acid by computational docking and structure modification

The development of myeloperoxidase (MPO) inhibitors has been conducted using flufenamic acid as a lead compound. Computational docking of the drug and its analogs in the MPO active site was first attempted. Several molecules were then synthesized and assessed using three procedures for the measurement of their inhibiting activity: (i) the taurine assay, (ii) the accumulation of compound II, and (iii) the LDL oxidation by ELISA. Most of the synthesized molecules had an activity in the same range as flufenamic acid but none of them were able to inhibit the MPO-dependent LDL oxidation. The experiments however gave some useful indications for a rational conception of MPO inhibitors.

Isoindole-imide compounds and compositions comprising and methods of using the same

This invention relates to isoindole-imide compounds, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.