58775-63-6Relevant academic research and scientific papers
A Unique Skeletal Rearrangement of a Bicyclo[33.1]nonanetrione to a Tetrahydroquinolin-2(1 H)-one System
Shen, Qi,Liu, Fang,Zhang, Yu-Chao,Wang, Jie,Zhang, Lei,Wang, Yue,Xu, Hong-Xi,Shao, Zhuzhou,Cao, Yang,Wu, Jing,Liang, Yong,Li, Jian-Xin
supporting information, p. 1711 - 1716 (2018/07/06)
The unexpected formation of a 4-hydroxytetrahydroquinolin-2(1 H)-one from a bicyclo[3.3.1]nonanetrione system and an amino alcohol in the presence of TsOH is reported. The mechanism of this transformation was studied by DFT calculations. The reaction provides an entry to the synthesis of highly functionalized 4-hydroxytetrahydroquinolin-2(1 H)-ones.
Modular Total Syntheses of Hyperforin, Papuaforins A, B, and C via Gold(I)-Catalyzed Carbocyclization
Bellavance, Gabriel,Barriault, Louis
, p. 7215 - 7230 (2018/05/23)
The remarkable biological activities of polyprenylated polycyclic acylphloroglucinols (PPAPs) combined with their highly oxygenated and densely functionalized frameworks have stimulated the interest of synthetic organic chemists over the past decade. Here
A total synthesis of sarcandralactone A: A general, concise, RCM enabled approach to lindenanolide sesquiterpenoids
Ramesh, Subburethinam,Mehta, Goverdhan
, p. 3941 - 3944 (2015/06/08)
A total synthesis of lindenane-type sesquiterpenoid natural product sarcandralactone A and its close sibling 5-epi-shizukanolide has been accomplished through a concise strategy in which a one-pot γ-lactone annulation and a RCM reaction constitute pivotal
Total syntheses of hyperforin and papuaforinsA-C, and formal synthesis of nemorosone through a gold(I)-catalyzed carbocyclization
Bellavance, Gabriel,Barriault, Louis
supporting information, p. 6701 - 6704 (2014/07/08)
The remarkable biological activities of polyprenylated polycyclic acylphloroglucinols (PPAPs) combined with their highly decorated bicyclo[3.3.1]nonane-2,4,9-trione frameworks have inspired synthetic organic chemists over the last decade. The concise tota
Direct Formation of the Steroid Nucleus by a Biomimetic Cyclization
Johnson, William S.,McCarry, Brian E.,Markezich, R. L.,Boots, Sharon G.
, p. 352 - 359 (2007/10/02)
The aim of this study was to synthesize the trienynol 3 and to study its cyclization.The substrate was synthesized by a convergent route, the key step being the stereoselective Wittig-Schlosser condensation of the known aldehyde 19 with the phosphorane 18
