587869-87-2Relevant academic research and scientific papers
A → J prostaglandin swap: A new tactic for cyclopentenone prostaglandin synthesis
Zanoni, Giuseppe,Castronovo, Francesca,Perani, Eleonora,Vidari, Giovanni
, p. 6803 - 6805 (2003)
A practical methodology for the synthesis of J-type prostaglandins has been developed starting from the well-consolidated approaches established for the synthesis of A-type prostaglandins. An efficient 1,3-allylic transposition of the C-9 hydroxyl group o
First enantioselective total synthesis of (8S,12R,15S)-prostaglandin J2
Zanoni, Giuseppe,Porta, Alessio,de Toma, Quintino,Castronovo, Francesca,Vidari, Giovanni
, p. 6437 - 6439 (2007/10/03)
Enantioselective synthesis of natural PGJ2 has been accomplished for the first time starting from the commercially available enantiopure aldehyde 7 in 10% overall yield. The key reaction was a novel prostaglandin class interconversion, i.e., an
