58791-89-2Relevant academic research and scientific papers
Dye-sensitized hematite compososite photocatalyst and its photocatalytic performance of aerobic annulation
Huang, Dong-Liang,Zhang, Peng-Li,Qu, Ling-Ling,Chen, Qiu-Yun
, p. 132 - 136 (2018)
A visible light initiated catalyst (DP-pfa@Fe2O3) is synthesized and used as a photocatalyst for the synthesis of pyrazoles under mild reaction conditions. Holes (h+) and [rad] OH are the essential for the light-induced th
Preparation method of 5-amino-4-cyanopyrazole
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Paragraph 0010; 0011; 0035; 0036, (2020/06/20)
The invention belongs to the field of organic chemistry, relates to a preparation method of 5-amino-4-cyanopyrazole, and discloses a preparation method of 5-amino-4-cyanopyrazole. According to the invention, a series of 5-amino-4-cyanopyrazole are prepare
Regioselective Synthesis of Highly Functionalized Pyrazoles from N-Tosylhydrazones
Zhang, Qian,Tang, Meng
supporting information, (2019/03/19)
A regioselective synthesis of highly functionalized pyrazoles from N-tosylhydrazones was developed. The reaction was general for a wide range of substrates and demonstrated excellent tolerance to a variety of substituents, and the method has been successfully applied to the formal synthesis of ibrutinib.
Visible-light photocatalytic aerobic annulation for the green synthesis of pyrazoles
Ding, Ya,Zhang, Te,Chen, Qiu-Yun,Zhu, Chunyin
supporting information, p. 4206 - 4209 (2016/09/09)
A selective and high yielding synthesis of polysubstituted pyrazoles through a VLPC (visible light photoredox catalysis)-promoted reaction of hydrazine with Michael acceptors is reported. The method employs very mild reaction conditions and uses air as the terminal oxidant, which makes the process environmentally benign. Different types of Michael acceptors with various substituents can undergo the reaction to afford corresponding pyrazoles in good to excellent yields. The reaction is proposed to go through VLPC-promoted oxidation of hydrazine to diazene followed by its addition to Michael acceptors, other than the conventional condensation of hydrazine with a carbonyl.
