478533-65-2

Upstream product

• 19350-69-7 4-chlorobenzaldehyde p-toluenesulfonylhydrazone 
• 121-45-9 phosphorous acid trimethyl ester 
• 104-88-1 4-chlorobenzaldehyde 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 56119-89-2 1-methyl-3-(4-chlorophenyl)-5-phenylpyrazole 
• 1515922-00-5 C₁₆H₁₂ClFN₂ 
• 58791-89-2 5-amino-3-(4-chlorophenyl)-1-methyl-1H-pyrazole-4-carbonitrile 

Relevant academic research and scientific papers

Regioselective synthesis of 1,3,5-Trisubstituted Pyrazoles from N-Alkylated Tosylhydrazones and terminal Alkynes

An efficient synthesis of 1,3,5-trisubstituted pyrazoles from Nalkylated tosylhydrazones and terminal alkynes was developed. The protocol was applied to a wide range of substrates and demonstrated excellent tolerance to a variety of substituents, includin

One-pot synthesis of N-alkyl sulfonyl hydrazones by dialkyl acetylenedicarboxylate-mediated reaction of trialkylphosphites with sulfonyl hydrazones

Stable derivatives of N-alkyl sulfonyl hydrazone were obtained in excellent yields from the reaction between electron-deficient acetylenic ester compounds and sulfonyl hydrazones in the presence of trialkylphosphites in dichloromethan at room temperature.