588-22-7

Usage

Uses

Used in Chemical Synthesis:
3,4-D is used as a key component in the synthesis of layered organic-inorganic nanohybrid materials, such as zinc-aluminum-3,4-dichlorophenoxyacetate. This application takes advantage of its chemical properties to create innovative materials with potential uses in various industries.
Used in Agriculture:
In the agricultural industry, 3,4-D is used as a herbicide for controlling the growth of broadleaf plants and weeds. Its effectiveness in targeting specific plant species without harming crops makes it a valuable tool for farmers and growers, helping to increase crop yields and maintain the quality of agricultural products.
Used in Environmental Management:
3,4-D is also utilized in environmental management for the control of invasive plant species that can disrupt ecosystems and negatively impact native flora and fauna. By selectively targeting these invasive plants, 3,4-D helps to preserve the balance of natural habitats and protect biodiversity.
Used in Research and Development:
In the field of research and development, 3,4-D serves as a starting material for the creation of new compounds and formulations with improved herbicidal properties. Scientists and chemists use it to develop more effective and environmentally friendly herbicides, contributing to the ongoing efforts to create sustainable agricultural practices.

InChI:InChI=1/C8H6Cl2O3/c9-6-2-1-5(3-7(6)10)13-4-8(11)12/h1-3H,4H2,(H,11,12)

Upstream product

• 32026-08-7 2-(3,4-dichlorophenoxy)acetamide 
• 39975-26-3 sodium 3,4-dichlorophenoxide 
• 105-36-2 ethyl bromoacetate 
• 95-77-2 3,4-dichlorophenol 
• 62855-72-5 ethyl 2-(3,4-dichlorophenoxy)acetate 

Downstream Products

• 62855-72-5 ethyl 2-(3,4-dichlorophenoxy)acetate 
• 52696-40-9 (3,4-Dichloro-phenoxy)-acetic acid 1-(3-chloro-4-trifluoromethyl-phenyl)-3,3-dimethyl-ureidomethyl ester 
• 113912-89-3 2-(3,4-Dichloro-phenoxy)-N-((R)-1-hydroxymethyl-propyl)-acetamide 
• 113912-90-6 2-(3,4-Dichloro-phenoxy)-N-((S)-1-hydroxymethyl-propyl)-acetamide 
• 99239-67-5 2-(3,4-Dichloro-phenoxy)-N-methyl-N-((1R,2S)-2-pyrrolidin-1-yl-cyclohexyl)-acetamide 
• 15422-26-1 N-(4-Chloro-phenyl)-2-(3,4-dichloro-phenoxy)-acetamide 
• 15422-29-4 N-(4-Chloro-benzyl)-2-(3,4-dichloro-phenoxy)-acetamide 
• 15422-28-3 N-(3-Chloro-benzyl)-2-(3,4-dichloro-phenoxy)-acetamide 
• 122-59-8 2-phenoxyacetic acid 
• 891980-85-1 C₁₅H₁₂Cl₂N₂O₃ 
• 891973-82-3 C₁₄H₁₁Cl₂N₃O₃ 
• 69764-13-2 2-({[(3,4-dichlorophenyl)oxy]acetyl}amino)benzoic acid 
• 69764-14-3 4-Chloro-2-[2-(3,4-dichloro-phenoxy)-acetylamino]-benzoic acid 
• 64673-07-0 2-(3,4-dichloro-phenoxy)-ethanol 

Relevant academic research and scientific papers

NURR1 RECEPTOR MODULATORS

Described herein, inter alia, are Nurr1 receptor modulators and uses thereof. In an aspect is provided a method for treating a disease associated with dysregulation and/or degeneration of dopaminergic neurons in the central nervous system of a subject in need thereof, the method including administering to the subject in need thereof a therapeutically effective amount of a compound described herein.

CHEMCICAL COMPOUNDS

The invention is directed to substituted pyrrolidine derivatives. Specifically, the invention is directed to compounds according to Formula III: wherein A, B, L1, L2, L3, R1, R2, R3, R4, R5, R6, R9, R10, R30, Y1, Y2, z2, z4, z5, and z6 are as defined herein, and salts thereof. The compounds of the invention are inhibitors of the ATF4 pathway and can be useful in the treatment of cancer, pre-cancerous syndromes and diseases associated with activated unfolded protein response pathways, such as Alzheimer's disease, spinal cord injury, traumatic brain injury, ischemic stroke, stroke, diabetes, Parkinson disease, Huntington's disease, Creutzfeldt-Jakob Disease, and related prion diseases, progressive supranuclear palsy, amyotrophic lateral sclerosis, myocardial infarction, cardiovascular disease, inflammation, fibrosis, chronic and acute diseases of the liver, chronic and acute diseases of the lung, chronic and acute diseases of the kidney, chronic traumatic encephalopathy (CTE), neurodegeneration, dementia, cognitive impairment, atherosclerosis, ocular diseases, arrhythmias, in organ transplantation and in the transportation of organs for transplantation. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting the ATF4 pathway and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

An Efficient One-Pot Synthesis of 2-(Aryloxyacetyl)cyclohexane-1,3-diones as Herbicidal 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, HPPD) is an important target for new bleaching herbicides discovery. As a continuous work to discover novel crop selective HPPD inhibitor, a series of 2-(aryloxyacetyl)cyclohexane-1,3-diones were rationally designed and synthesized by an efficient one-pot procedure using N,N′-carbonyldiimidazole (CDI), triethylamine, and acetone cyanohydrin in CH2Cl2. A total of 58 triketone compounds were synthesized in good to excellent yields. Some of the triketones displayed potent in vitro Arabidopsis thaliana HPPD (AtHPPD) inhibitory activity. 2-(2-((1-Bromonaphthalen-2-yl)oxy)acetyl)-3-hydroxycyclohex-2-en-1-one, II-13, displayed high, broad-spectrum, and postemergent herbicidal activity at the dosage of 37.5-150 g ai/ha, nearly as potent as mesotrione against some weeds. Furthermore, II-13 showed good crop safety against maize and canola at the rate of 150 g ai/ha, indicating that II-13 might have potential as a herbicide for weed control in maize and canola fields. II-13 is the first HPPD inhibitor showing good crop safety toward canola.

THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE

The present invention relates to substituted thiadiazole compounds of the formula (I) and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.