58849-84-6Relevant academic research and scientific papers
THE TRAPPING OF SULFENIC ACIDS FROM PENICILLIN SULFOXIDES. ARYL MERCAPTANS
Micetich, Ronald G.,Maiti, Samarendra N.,Tanaka, Motoaki,Yamazaki, Tomio,Ogawa, Kazuo
, p. 1403 - 1409 (2007/10/02)
Aryl mercaptans, unlike heterocyclic mercaptans, reacted exceptionally slowly with penicillin sulfoxides.These reactions are affected by the substituent at the C-6 position of the penam, and by the nature of the ester group at the C-3 position.The unsym- azetidinone disulfides obtained from these reactions, unlike those from heterocyclic mercaptans, did not react with halogenating agents such as cupric chloride.
PENICILLIN SULFOXIDE THERMOLYSIS IN TRIMETHYL ORTHOACETATE
Micetich, Ronald G.,Singh, Rajeshwar,Morin, Robert B.
, p. 809 - 812 (2007/10/02)
The thermolysis of trichloroethyl 6-phenoxyacetamidopenicillanate sulfoxide in trimethyl orthoacetate gave four -lactam cleaved products.
THE TRAPPING OF SULFENIC ACIDS FROM PENICILLIN SULFOXIDES. ETHYL 2-MERCAPTOACETATE
Micetich, Ronald G.,Maiti, Samarendra N.,Tanaka, Motoaki,Yamazaki, Tomio,Ogawa, Kazuo
, p. 3179 - 3182 (2007/10/02)
The thermolysis of trichloroethyl 6-phenoxyacetamido penicillanate sulfoxide and ethyl 2-mercaptoacetate in toluene gave the unsym-azetidinone disulfide (β,γ-isomer) in 65percent yield.With added catalytic amounts of N,N-dimethylaniline the α,β-isomer was
