58849-84-6Relevant academic research and scientific papers
THE TRAPPING OF SULFENIC ACIDS FROM PENICILLIN SULFOXIDES. ARYL MERCAPTANS
Micetich, Ronald G.,Maiti, Samarendra N.,Tanaka, Motoaki,Yamazaki, Tomio,Ogawa, Kazuo
, p. 1403 - 1409 (2007/10/02)
Aryl mercaptans, unlike heterocyclic mercaptans, reacted exceptionally slowly with penicillin sulfoxides.These reactions are affected by the substituent at the C-6 position of the penam, and by the nature of the ester group at the C-3 position.The unsym- azetidinone disulfides obtained from these reactions, unlike those from heterocyclic mercaptans, did not react with halogenating agents such as cupric chloride.
THE TRAPPING OF SULFENIC ACIDS FROM PENICILLIN SULFOXIDES. ETHYL 2-MERCAPTOACETATE
Micetich, Ronald G.,Maiti, Samarendra N.,Tanaka, Motoaki,Yamazaki, Tomio,Ogawa, Kazuo
, p. 3179 - 3182 (2007/10/02)
The thermolysis of trichloroethyl 6-phenoxyacetamido penicillanate sulfoxide and ethyl 2-mercaptoacetate in toluene gave the unsym-azetidinone disulfide (β,γ-isomer) in 65percent yield.With added catalytic amounts of N,N-dimethylaniline the α,β-isomer was
PENICILLIN SULFOXIDE THERMOLYSIS IN TRIMETHYL ORTHOACETATE
Micetich, Ronald G.,Singh, Rajeshwar,Morin, Robert B.
, p. 809 - 812 (2007/10/02)
The thermolysis of trichloroethyl 6-phenoxyacetamidopenicillanate sulfoxide in trimethyl orthoacetate gave four -lactam cleaved products.
