58863-86-8Relevant academic research and scientific papers
Four-Component Synthesis of Phosphonium Salts: Application Toward an Alternative Approach to Cross-Coupling for the Synthesis of Bis-Heteroarenes
Chen, Yi-Ru,Reddy, Ganapuram Madhusudhan,Hong, Shao-Hao,Wang, Ying-Zheng,Yu, Jhen-Kuei,Lin, Wenwei
, p. 5106 - 5110 (2017)
A series of stable phosphonium salts have been synthesized via a novel four-component reaction of an arene nucleophile, 2-heteroatom substituted aryl aldehyde, and phosphine in presence of an acid. The phosphonium salts thus obtained were utilized for the synthesis of a variety of bis-heteroarenes, providing an efficient alternative method to the classical cross-coupling strategies.
Carbocatalysed Oxidative C sp 2 -C sp 2 Homocouplings of Benzo-Fused Heterocycles
Wirtanen, Tom,M?kel?, Mikko K.,Sarfraz, Jawad,Ihalainen, Petri,Hietala, Sami,Melchionna, Michele,Helaja, Juho
supporting information, p. 3718 - 3726 (2016/01/25)
Appropriate and fine-tuned treatments of amorphous carbon (AC) involving aqua regia or concentrated HNO3 lead to oxidised carbon materials (oAC) which are able to catalyse 2,2′- and 3,3′-homocouplings of various functionalised indoles with outs
Palladium-catalyzed coupling of ortho-alkynylanilines with terminal alkynes under aerobic conditions: Efficient synthesis of 2,3-disubstituted 3-alkynylindoles
Yao, Bo,Wang, Qian,Zhu, Jieping
supporting information, p. 12311 - 12315 (2013/02/23)
Two nucleophiles, one triple bond: Under aerobic conditions, palladium-catalyzed direct coupling of o-alkynylanilines and terminal alkynes took place smoothly to afford the 2,3-disubstituted 3-alkynylindoles 3 in good to excellent yields. The intermediate A was characterized and a retro-aminopalladation of B was observed for the first time. Copyright
Nitrenium ions. ? reactions of N,N-dimethyl-p-benzoyloxyaniline-iminium chloride with indoles and indolizines. X-ray structure of unexpected [2-chloro-4-(4-dimethylaminophenyl-ONN-azoxy)-phenyl]dimethylamine (azoxy derivative)
Greci, Lucedio,Castagna, Riccardo,Carloni, Patricia,Stipa, Pierluigi,Rizzoli, Corrado,Righi, Lara,Sgarabotto, Paolo
, p. 3768 - 3771 (2007/10/03)
N,N-Dimethyl-p-nitrosoaniline reacts with benzoyl chloride affording a complex salt containing a cation, a hybrid between a nitrenium ion and an iminium ion. The salt reacts with nucleophiles (indoles, indolizines) yielding compounds characterized by a new carbon-nitrogen bond, derived from the nitrenium ion form. According to the type of nucleophile, the reaction, to differing extents, is in competition with an electron transfer process which leads to the formation of the dimer of the nucleophile and of the azoxy corresponding to the N,N-dimethyl-p-nitrosoaniline. In one of the reactions studied, a chlorinated azoxy derivative was also isolated, and its structure was elucidated by X-ray analysis.
