58863-88-0Relevant academic research and scientific papers
Gold/Copper-Co-catalyzed Tandem Reactions of 2-Alkynylanilines: A Synthetic Strategy for the C2-Quaternary Indolin-3-ones
Li, Yi-Jin,Yan, Na,Liu, Chun-Hua,Yu, Yang,Zhao, Yu-Long
supporting information, p. 1160 - 1163 (2017/03/14)
A new strategy for direct and highly efficient synthesis of 2,3′-bisindolin-3-ones has been developed via a gold/copper-co-catalyzed tandem reactions of 2-alkynylanilines using TBHP as the terminal oxidant and oxygen-atom source. The single-step process involves a novel tandem intermolecular nucleophilic addition, intramolecular cyclization/oxidative cross-dehydrogenative coupling where up to four new bonds and two indole rings were created simultaneously in one-pot manner. The reaction features a broad substrate scope, good functional group tolerance, and high atom-economy.
Oxidation of Indole Substrates by Oxodiperoxomolybdenum· Trialkyl(aryl)-phosphine Oxide Complexes
Altinis Kiraz, Christine I.,Emge, Thomas J.,Jimenez, Leslie S.
, p. 2200 - 2202 (2007/10/03)
A series of oxodiperoxo molybdenum complexes MoO5· O=PR3·L, where R = Me, Et, Pr, Bu, or Ph, have been synthesized. The X-ray crystal structures for the complexes with triethylphosphine oxide and tripropylphosphine oxide as ligands were obtained. These complexes oxidize indoles to various indolone products depending on the substitution pattern of the indole substrate.
Electron Transfer Reactions. A Reinvestigation of the Chlorination of 1-Methyl-2-phenylindole with N-Chlorobenzotriazole. The Role of Oxygen and Oxygenated Solvent
Carloni, Patricia,Eberson, Lennart,Greci, Lucedio,Stipa, Pierluigi,Tosi, Giorgio
, p. 1779 - 1784 (2007/10/02)
1-Methyl-2-phenylindole (1, MPI-H) reacts with N-chlorobenztriazole (2, BT-Cl) to form the corresponding radical cation (MPI-H).+ which itself, or via the indolyl radical (MPI).+, formed by deprotonation of MPI-H.+, reacts with oxygen or a nucleophilic solvent leading to indoxyls 4-7.Cyclic voltammetric studies, as well as the oxidation of MPI-H with BT-Cl carried out in the EPR cavity, show that the radical cation MPI-H.+ dimerizes to give 3,3'-(MPI)2 8 which is transformed into the corresponding radical cation 3,3'-(MPI)2.+ in the reaction medium.The identi ty of this radical cation has been confirmed by oxidizing 3,3'-(MPI)2 directly.The formation of the radical cations MPI-H.+ and 3,3'-(MPI)2.+ has been monitored by UV-VIS spectroscopy and their decay rate constants measured.
New Aspects in the Chlorination of Indoles with 1-Chlorobenzotriazole and 1-Chloroisatin
Berti, C.,Greci, L.,Andruzzi, R.,Trazza, A.
, p. 4895 - 4899 (2007/10/02)
2-Phenyl-, 1-methyl-2-phenyl-, and 2-phenyl-3-methylindole react with 1-chlorobenzotriazole and 1-chloroisatin to form essentially 3-chloroindoles.The composition of the products, which depends on the solvent used, suggests an electron-transfer process fo
