588672-40-6Relevant academic research and scientific papers
C(sp3)-H functionalizations of light hydrocarbons using decatungstate photocatalysis in flow
Deng, Yuchao,Fagnoni, Maurizio,Guthrie, Duncan,Laudadio, Gabriele,No?l, Timothy,Nun?, Manuel,Ravelli, Davide,Sun, Yuhan,Wal, Klaas Van Der
, p. 92 - 96 (2020/09/03)
Direct activation of gaseous hydrocarbons remains a major challenge for the chemistry community. Because of the intrinsic inertness of these compounds, harsh reaction conditions are typically required to enable C(sp3)-H bond cleavage, barring potential applications in synthetic organic chemistry. Here, we report a general and mild strategy to activate C(sp3)-H bonds in methane, ethane, propane, and isobutane through hydrogen atom transfer using inexpensive decatungstate as photocatalyst at room temperature. The corresponding carbon-centered radicals can be effectively trapped by a variety of Michael acceptors, leading to the corresponding hydroalkylated adducts in good isolated yields and high selectivity (38 examples).
Conjugate addition of nitroalkanes to N-substituted maleimides. Synthesis of 3-alkylsuccinimides and pyrrolidines
Ballini, Roberto,Bosica, Giovanna,Cioci, Gianluca,Fiorini, Dennis,Petrini, Marino
, p. 3603 - 3608 (2007/10/03)
3-Alkylidenesuccinimides obtained by conjugate addition of nitroalkanes to N-substituted maleimides can be reduced to the corresponding 3-alkyl derivatives by catalytic hydrogenation. 3-Alkylsuccinimides can be further reduced using BH3·Me
