588720-36-9Relevant articles and documents
Phosphodiesterase inhibitor, and applications thereof
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Paragraph 0243; 0245-0249, (2018/09/08)
The invention belongs to the technical field of medicine, and more specifically relates to a phosphodiesterase 9 (PDE9) inhibitor represented by formula I, and pharmaceutically acceptable salts, solvates, polymorphic substances, and isomers thereof, and also relates to medicinal preparations, and pharmaceutical compositions of the above compounds, and applications of the medicinal preparations andpharmaceutical compositions. The compounds and the pharmaceutically acceptable salts, solvates, polymorphic substances, and isomers can be used in treatment of phosphodiesterase 9 (PDE9) abnormal expression mediated related diseases.
NOVEL CHROMANE COMPOUND FOR THE TREATMENT OF PAIN DISORDERS
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Page/Page column 13, (2012/04/10)
The present invention relates to the compound N-[(3S)-5-(5-methoxypyrazin-2-yl)-3,4- dihydro-2H-chromen-3-yl]-6-[(2,2,2-trifluoroethoxy)methyl]pyridine-3-carboxamide, or a pharmaceutical composition comprising said compound and to the use of said compounds in therapy.
HETEROARYL SUBSTITUTED THIAZOLES
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Page/Page column 45, (2009/01/20)
The invention provides heteroaryl substituted thiazolo compounds of Formula I and II and pharmaceutically acceptable salts thereof. The variables A and R3 to R7 are defined herein. The invention also includes methods for preparing compounds and salts of Formula I and II. The present invention also includes pharmaceutical compositions containing heteroaryl substituted thiazolo compounds and methods for using heteroaryl substituted thiazolo compounds, including methods for using the compounds in the treatment of hepatitis C virus.