588727-85-9Relevant academic research and scientific papers
A highly efficient approach to 5-alkyl-5-hydroxymethyl substituted 4-O-benzyl tetramates
Paintner, Franz F.,Metz, Marcel,Bauschke, Gerd
, p. 627 - 630 (2007/10/03)
4-O-Benzyl-5-methoxycarbonyl tetramates readily available by 5-methoxycarbonylation of 4-O-benzyl tetramates undergo highly regioselective alkylations with various alkyl halides to give 5-alkyl-4-O-benzyl-5-methoxycarbonyl tetramates in high overall yields. These can be efficiently converted into 5-alkyl-5-hydroxymethyl substituted 4-O-benzyl tetramates and further into the respective tetramic acids.
