588728-53-4Relevant academic research and scientific papers
Synthetic approaches to the bottom half fragment for bryostatin 11
Nakagawa-Goto, Kyoko,Crimmins, Michael T.
, p. 1555 - 1558 (2011/08/05)
An approach towards the stereoselective synthesis of the bottom half fragment of bryostatin 11 is described. Key steps -include asymmetric aldol and Saksena-Evans reduction reactions -to construct multiple stereogenic centers and thioketalization-lactoniz
BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES
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Page/Page column 124; 129, (2009/05/28)
Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and utilizing the same.
A New Synthetic Approach to the C Ring of Known as Well as Novel Bryostatin Analogues
Wender, Paul A.,Koehler, Michael F. T.,Sendzik, Martin
, p. 4549 - 4552 (2007/10/03)
(Equation presented) A new approach to the synthesis of the C ring subunit of known and potential bryostatin analogues is described. The convergent approach, Illustrated above, requires fewer steps and offers greater flexibility In rapidly accessing diver
