58928-91-9

Upstream product

• 109-80-8 1.3-propanedithiol 
• 35583-17-6 3,9-bis(4-bromophenyl)-2,4,8,10-tetraoxaspiro[5.5]undecane 
• 873-75-6 4-bromobenzenemethanol 
• 57529-04-1 2-chloro-1,3-dithiane 
• 1122-91-4 4-bromo-benzaldehyde 
• 55605-27-1 (4-bromophenyl)methylenediacetate 
• 24856-58-4 1,1-dimethoxy-1-(4-bromophenyl)methane 

Downstream Products

• 104865-88-5 trimethyl 4-bromobenzoate 
• 1443982-44-2 4-dodecyl-1-(triethoxymethyl)benzene 
• 1443982-42-0 2,4,6,8-tetrakis(4-dodecylphenyl)[1,2-d:3,4-d′]bis(oxazole) 
• 1443982-40-8 4,8-bis(5-dodecylthien-2-yl)-2,6-bis(4-dodecylphenyl)benzo[1,2-d;4,5-d′]bis(oxazole) 
• 1443982-38-4 4,8-dibromo-2,6-bis(4-dodecylphenyl)benzo[1,2-d;3,4-d′]bis(oxazole) 
• 1443982-37-3 2,6-bis(4-dodecylphenyl)benzo[1,2-d;3,4-d′]bis(oxazole) 
• 1122-91-4 4-bromo-benzaldehyde 
• 111997-80-9 2-(4-Bromphenyl)-1,3-dithian-2-ylium-tribromid 
• 117417-13-7 2-[4-((E)-2-Bromo-vinyl)-phenyl]-[1,3]dithiane 

Relevant academic research and scientific papers

An expedient carbon–sulfur bond formation explored through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds

A facile carbon–sulfur bond formation was observed through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds. In a preliminary study, the synthesis and characterization of functionalized bio-polymer, cellulose sulph

Anodic oxidation of dithiane carboxylic acids: A rapid and mild way to access functionalized orthoesters

A new electrochemical methodology has been developed for the preparation of a wide variety of functionalized orthoesters under mild and green conditions from easily accessible dithiane derivatives. The new methodology also offers an unprecedented way to access tri(fluorinated) orthoesters, a class of compound that has never been studied before. This provides the community with a rapid and general method to prepare libraries of functionalized orthoesters from simple and readily available starting materials.

An uncommon use of irradiated flavins: Br?nsted acid catalysis

We present that thioacetalization of aldehydes can be induced by blue light irradiation in the presence of a catalytic amount of riboflavin tetraacetate (RFTA) under aerobic conditions. Several control experiments have suggested that the reaction is more

Dithioacetalization or thioetherification of benzyl alcohols using 9-mesityl-10-methylacridinium perchlorate photocatalyst

We report herein the use of 9-mesityl-10-methylacridinium perchlorate as the visible-light photocatalyst for dithioacetalization or thioetherification of benzyl alcohols in one pot using aerial dioxygen as a terminal oxidant. EPR analysis and Stern-Volmer

λ3-Iodanes as Visible Light Photocatalyst in Thioacetalization of Aldehydes

Introduction of an iodine(III) reagent as visible-light photocatalyst for chemoselective dithioacetalization has been the limelight of the current methodology. The mechanistic investigations reveal that the reactions proceeded via radical pathway upon lig

Synthesis of Chiral α-Aminosilanes through Palladium-Catalyzed Asymmetric Hydrogenation of Silylimines

The asymmetric hydrogenation of silylimines was first developed by using a palladium complex of a P-stereogenic diphosphine ligand as the catalyst, affording the valuable chiral α-aminosilanes with quantitative conversions and excellent enantioselectiviti

A 2 - substituted - 1, 3 - dithiane derivative of the preparation method

The invention provides a preparation method of a 2-substituted-1,3-dithiane derivative. The preparation method comprises the following steps: adding 1,3-dithiane (CAS:505-23-7) and 1,2-dichloroethane (DCE) or dichloromethane (DCM) into a reaction bottle, adding N-chlorosuccinimide (NCS) under ice-bath condition, and stirring for 0.5-1 h to prepare a 2-chloro-1,3-dithiane solution; and adding an aldehyde or ketone compound and a lewis acid catalyst into the above solution, and reacting to prepare the 2-substituted-1,3-dithiane derivative. By using the 1,3-dithiane solid and different types of aldehyde and keto-carbonyl compounds as raw material and using one or more of ferric trichloride, boron trifluoride diethyl etherate, methanesulfonic acid, aluminum trichloride, ferrous chloride and nickel chloride as catalysts, preparation of the 2-substituted-1,3-dithiane derivative is realized. The catalysts used in the invention are cheap and easily available, dosage of the catalysts is low and pollution of the catalysts is little. The solid raw materials used in the invention can avoid use of fetid toxic 1,3-dimercaptopropane with strong volatility, and the purpose of protecting an experimenter's body and reducing environmental pollution is realized. In addition, the preparation method has advantages of mild reaction condition, high yield, simple operation and the like.

Visible-light promoted dithioacetalization of aldehydes with thiols under aerobic and photocatalyst-free conditions

A novel photocatalyst-free visible-light-mediated dithioacetalization of aldehydes and thiols has been developed. This protocol is operationally simple, mild and atom-economical, which provides an environmental benign access to dithioacetals at room temperature under aerobic conditions.

Pot-economy autooxidative condensation of 2-Aryl-2-lithio-1,3-dithianes

The autoxidative condensation of 2-aryl-2-lithio-1,3-dithianes is here reported. Treatment of 2-aryl-1,3-dithianes with n-BuLi in the absence of any electrophile leads to condensation of three molecules of 1,3-dithianes and formation of highly functionalized α-thioether ketones orthothioesters in 51-89% yields upon air exposure. The method was further expanded to benzaldehyde dithioacetals, affording corresponding orthothioesters and α-thioether ketones in 48-97% yields. The experimental results combined with density functional theory studies support a mechanism triggered by the autoxidation of 2-aryl-2-lithio-1,3-dithianes to yield a highly reactive thioester that undergoes condensation with two other molecules of 2-aryl-2-lithio-1,3-dithiane.

Preparing method of 2-substituted-1,3-dithiane derivative

The invention belongs to the technical field of organic synthesis, and particularly discloses a preparing method of a 2-substituted-1,3-dithiane derivative. The preparing method comprises the following steps of adding substrate aldehyde, 1,3-dimercaptopro