58931-20-7

Upstream product

• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 56039-06-6 methyl 5-(cyanomethyl)-1H-imidazole-4-carboxylate 
• 22224-38-0 1,2,3,5-tetra-O-benzoyl-β-D-ribofuranose 

Downstream Products

• 56039-11-3 3-deazaguanosine 
• 91713-22-3 1-amino-3-deazaguanosine 
• 862973-70-4 1-((2R,3R,4R,5R)-3,4-Bis-benzoyloxy-5-benzoyloxymethyl-tetrahydro-furan-2-yl)-5-(cyano-fluoro-methyl)-1H-imidazole-4-carboxylic acid methyl ester 
• 663616-68-0 1,5-dihydro-6-[(phenoxyacetyl)amino]-1-(β-D-ribofuranosyl)-4H-imidazo[4,5-c]pyridin-4-one 
• 663616-70-4 1-{5'-O-[bis(4-methoxyphenyl)phyenylmethyl]-β-D-ribofuranosyl}-1,5-dihydro-6-[(phenoxyacetyl)amino]-4H-imidazo[4,5-c]pyridin-4-one 
• 663616-72-6 1-{5'-O-[bis(4-methoxyphenyl)phyenylmethyl]-β-D-ribofuranosyl}-N⁶(phenoxyacetyl)-1H-imidazo[4,5-c]pyridin-6-amine 
• 663616-75-9 1-{5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[tris(1-methylethyl)silyl]-β-D-ribofuranosyl}-4-[(diphenylcarbamoyl)oxy]-N⁶(phenoxyacetyl)-1H-imidazo[4,5-c]pyridin-6-amine 

Relevant academic research and scientific papers

Synthesis and enzymic hydrolysis of oligoribonucleotides incorporating 3-deazaguanosine: The importance of the nitrogen-3 atom of single conserved guanosine residues on the catalytic activity of the hammerhead ribozyme

Four base-modified hammerhead ribozyme/substrate complexes were constructed in which single guanosine (1) residues were replaced by 3-deazaguanosine (2) in the positions G5, G8, G L2.1, and G12. The base-modifie

Electrophilic fluorination of 5-(cyanomethyl)imidazole-4-carboxylate nucleosides: Facile entry to 3-fluoro-3-deazaguanosine analogues

A facile and efficient methodology is described for the synthesis of 3-fluoro-3-deazaguanosines based on a novel electrophilic fluorination of 5-(cyanomethyl)imidazole-4-carboxylate nucleosides. This general methodology can be readily applied to the synth