58960-00-2

Basic information

• Product Name: 2-methyl-3,4-dihydro-2H-1,4-benzothiazine
• Synonyms: 2-methyl-3,4-dihydro-2H-1,4-benzothiazine;3,4-Dihydro-2-methyl-2H-1,4-benzothiazine;2H-1,4-Benzothiazine, 3,4-dihydro-2-methyl-
• CAS NO: 58960-00-2
• Molecular Formula: C₉H₁₁NS
• Molecular Weight: 165.25534
• Mol File: 58960-00-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-methyl-3,4-dihydro-2H-1,4-benzothiazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-3,4-dihydro-2H-1,4-benzothiazine(58960-00-2)
• EPA Substance Registry System: 2-methyl-3,4-dihydro-2H-1,4-benzothiazine(58960-00-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 58960-00-2(Hazardous Substances Data)

Upstream product

• 106-95-6 allyl bromide 
• 137-07-5 2-amino-benzenethiol 
• 7028-57-1 2-methyl-3,4-dihydro-3-oxo-2H-1,4-benzothiazine 
• 90921-53-2 2,2-dimethyl-3-oxo-2,3-dihydro-4H-1,4-benzothiazine 

Downstream Products

• 87012-00-8 4-benzoyl-2-methyl-2,3-dihydro-1,4-benzothiazine 

Relevant articles and documents

SINTESI ED ATTIVITA ANTIINFIAMMATORIA DI ALCUNI DERIVATI 1,4-BENZOTIAZINICI

A new series of dihydro-4H-1,4-benzothiazine derivatives was prepared.These compounds were obtained by reductive N-alkylation reaction with sodium borohydride in acetic acid of the corresponding 4H-1,4-benzothiazine.Some of the latter compounds were synthesized by a new synthetic method employing 2-aminobenzenethiol and alkynes as starting material. - Preliminary pharmacological data on the antiinflammatory activity of these compounds by using carrageenin paw edema assay are reported.

Eliminative Ring Fission of 4-Acyl-2,3-dihydro-4H-1,4-benzothiazines

The behavior of 4-acyl-2,3-dihydro-1,4-benzothiazines 1-11 upon treatment with lithium diisopropylamide (LDA) in THF at -78 deg C has been examined.Very marked differences have been observed.Whereas unsubstituted and monosubstituted derivatives (1-4) read