58980-39-5

Basic information

• Product Name: 6,7,8,9-Tetrahydro-5-thia-8-aza-benzocycloheptene
• Synonyms: 6,7,8,9-Tetrahydro-5-thia-8-aza-benzocycloheptene;1,4-Benzothiazepine, 2,3,4,5-tetrahydro-;2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine;2,3,4,5-Tetrahydro-1,4-benzothiazepine
• CAS NO: 58980-39-5
• Molecular Formula: C9H11NS
• Molecular Weight: 165.25534
• Mol File: 58980-39-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 282℃
• Flash Point: 125℃
• Appearance: /
• Density: 1.105
• Storage Temp.: 2-8°C
• PKA: 8.44±0.20(Predicted)
• CAS DataBase Reference: 6,7,8,9-Tetrahydro-5-thia-8-aza-benzocycloheptene(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7,8,9-Tetrahydro-5-thia-8-aza-benzocycloheptene(58980-39-5)
• EPA Substance Registry System: 6,7,8,9-Tetrahydro-5-thia-8-aza-benzocycloheptene(58980-39-5)

Safety Data

• Hazardous Substances Data: 58980-39-5(Hazardous Substances Data)

Usage

General Description

6,7,8,9-Tetrahydro-5-thia-8-aza-benzocycloheptene, also known as tetrahydrobenzothiophene, is a heterocyclic compound with a molecular formula C9H9NS. It is a colorless liquid with a very strong odor, and it is used as a pesticide and in the production of synthetic fibers, rubber, and plastics. Tetrahydrobenzothiophene is also used as a solvent and as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is a highly flammable substance and can be hazardous if not handled and stored properly. Additionally, it is important to note that tetrahydrobenzothiophene may have toxic effects on aquatic organisms, and precautions should be taken to prevent its release into the environment.

Upstream product

• 104864-66-6 2-(2-Amino-ethylsulfanyl)-benzoic acid methyl ester 
• 4892-02-8 Methyl thiosalicylate 
• 147-93-3 Thiosalicylic acid 
• 7757-82-6 sodium sulfate 
• 103693-32-9 4,5-Dihydro-1,4-benzothiazepin-3(2H)-one 
• 411211-27-3 2-(2-amino-ethylsulfanyl)-benzoic acid ethyl ester 
• 14944-00-4 3,4-dihydro-1,4-benzothiazepin-5(2H)-one 

Downstream Products

• 58980-41-9 4-benzoyl-2,3,4,5-tetrahydro-benzo[f][1,4]thiazepine 
• 769858-09-5 2,3,4,5-tetrahydro-1λ6,4-benzothiazepine 1,1-dioxide 
• 24187-79-9 2,3-dihydro-5H-benzo[f][1,4]thiazepine-4-carboxylic acid anilide 

Relevant articles and documents

HISTONE ACETYLTRANSFERASE (HAT) INHIBITOR AND USE THEREOF

The present invention relates to a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the treatment of various HAT-related diseases or conditions.

COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE

The invention relates to the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2 and X are as defined in the description and claims, which are useful for the treatment or prophylaxis of RSV infection.

Therapeutic 1,4-thiazepines

Compounds of formula I STR1 in which n=0, 1 or 2; R1, R2, R6 and R7 independently represent H or alkyl (optionally substituted by one or more halo); R3 and R4 independently represent H or a