59019-35-1Relevant academic research and scientific papers
124. The Reaction of Singlet Oxygen with 1,3-dimethylindole in the Presence of Aldehydes. Formation of 1,2,4-trioxanes
Jefford, Charles W.,Jaggi, Danielle,Boukouvalas, John,Kohmoto, Shigeo,Bernardinelli, Gerald
, p. 1104 - 1111 (1984)
The dye-sensitized photo-oxygenation of 1,3-dimethylindole in the presence of aldehydes initially generates a zwitterionic peroxide which condenses with the carbonyl function to give the corresponding cis-fused 1,2,4-trioxanes.Acetaldehyde gives a pair of
Aerobic C–C Bond Cleavage of Indoles by Visible-Light Photoredox Catalysis with Ru(bpy)32+
Ji, Xiaochen,Li, Dongdong,Wang, Zhongzhen,Tan, Muyun,Huang, Huawen,Deng, Guo-Jun
, p. 6652 - 6659 (2017/12/15)
Photoredox catalysis with Ru(bpy)32+ (2,2′-bipyridine) has been used to enable the activation of oxygen in the aerobic C–C cleavage/oxygenation reaction of indoles. A number of indole substrates that contain various functional groups were successfully employed in the reaction to give a wide range of ortho-aminobenzaldehyde derivatives. These products can then be used as versatile building blocks for further synthetic modifications. Mechanistic studies suggest that the reaction proceeds through a radical pathway.
DYE-SENSITIZED PHOTOOXIDATION OF 1-METHYLINDOLYL-3-ACETIC ACID
Amat-Guerri, Francisco,Lopez-Gonzalez, M. Mar C.,Martinez-Utrilla, Roberto
, p. 3749 - 3752 (2007/10/02)
The structure of the products constituting the complex mixture afforded by the entitled reaction is similar to that proceeding from the N-unmethylated acid and supports the presumed mechanistic analogy with the enzymatic oxidation.
