59021-52-2Relevant academic research and scientific papers
An efficient synthesis of 3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one derivatives via an iminophosphorane
He, Ping,Yan, Yan-Mei,Ding, Ming-Wu
, p. E93-E97 (2014/11/07)
The iminophosphorane (3), obtained from reaction of ethyl 3-amino-4-cyano-1-phenyl-1H-pyrrole-2-carboxylate (2) with triphenylphosphine, hexachloroethane, and triethylamine, reacted with aromatic isocyanates to give carbodiimides (4). Further reaction of
On the Synthesis of 3-amino-pyrroles by Thorpe-Ziegler-Cyclization
Gewald, K.,Schaefer, H.,Bellmann, P.,Hain, U.
, p. 491 - 496 (2007/10/02)
N-Aryl and alkylaminomethylene cyanacetic acid derivatives 1 react with α-halogencarbonyl compounds 2 in the presence of potassium carbonate/sodium ethoxide to yield the substituted 3-amino-pyrroles 6.Using the same principle of cyclization pyrrole deriva
