590371-97-4 Usage
Uses
Used in Pharmaceutical Industry:
4-BROMO-3-(TRIFLUOROMETHYL)QUINOLINE is used as an intermediate in the synthesis of various pharmaceutical drugs and agrochemicals, contributing to the development of new therapeutic agents and agricultural products.
Used in Organic Synthesis:
4-BROMO-3-(TRIFLUOROMETHYL)QUINOLINE is used as a building block in the production of other organic compounds, leveraging its reactivity to create a wide range of chemical entities with potential applications in various fields.
Used in Research and Development:
Due to its unique structure and reactivity, 4-BROMO-3-(TRIFLUOROMETHYL)QUINOLINE is utilized in research and development for exploring new chemical reactions and pathways, leading to the discovery of innovative molecules with specific biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 590371-97-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,0,3,7 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 590371-97:
(8*5)+(7*9)+(6*0)+(5*3)+(4*7)+(3*1)+(2*9)+(1*7)=174
174 % 10 = 4
So 590371-97-4 is a valid CAS Registry Number.
InChI:InChI=1S/C10H5BrF3N/c11-9-6-3-1-2-4-8(6)15-5-7(9)10(12,13)14/h1-5H
590371-97-4Relevant articles and documents
Recommendable routes to trifluoromethyl-substituted pyridine- and quinolinecarboxylic acids
Cottet, Fabrice,Marull, Marc,Lefebvre, Olivier,Schlosser, Manfred
, p. 1559 - 1568 (2003)
As part of a case study, rational strategies for the preparation of all ten 2-, 3-, or 4-pyridinecarboxylic acids and all nine 2-, 3-, 4-, or 8-quinolinecarboxylic acids bearing trifluoromethyl substituents at the 2-, 3-, or 4-position were elaborated. The trifluoromethyl group, if not already present in the precursor, was introduced either by the deoxygenative fluorination of suitable carboxylic acids with sulfur tetrafluoride or by the displacement of ring-bound bromine or iodine by trifluoromethylcopper generated in situ. The carboxy function was produced by treatment of organolithium or organomagnesium intermediates, products of halogen/metal or hydrogen/ metal permutation, with carbon dioxide. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
