588702-65-2 Usage
General Description
3-(Trifluoromethyl)quinoline-4-carboxylic acid is a chemical compound with the molecular formula C11H6F3NO2. It is a derivative of quinoline, a heterocyclic compound with a ring structure containing nitrogen. The presence of the trifluoromethyl group and carboxylic acid functionality makes this compound useful for various applications, including as a building block for the synthesis of pharmaceuticals and agrochemicals. It may also be used as a ligand in coordination chemistry or as a precursor in organic synthesis. The compound's properties and reactivity make it valuable in the development of new materials and bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 588702-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,8,7,0 and 2 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 588702-65:
(8*5)+(7*8)+(6*8)+(5*7)+(4*0)+(3*2)+(2*6)+(1*5)=202
202 % 10 = 2
So 588702-65-2 is a valid CAS Registry Number.
588702-65-2Relevant articles and documents
Recommendable routes to trifluoromethyl-substituted pyridine- and quinolinecarboxylic acids
Cottet, Fabrice,Marull, Marc,Lefebvre, Olivier,Schlosser, Manfred
, p. 1559 - 1568 (2007/10/03)
As part of a case study, rational strategies for the preparation of all ten 2-, 3-, or 4-pyridinecarboxylic acids and all nine 2-, 3-, 4-, or 8-quinolinecarboxylic acids bearing trifluoromethyl substituents at the 2-, 3-, or 4-position were elaborated. The trifluoromethyl group, if not already present in the precursor, was introduced either by the deoxygenative fluorination of suitable carboxylic acids with sulfur tetrafluoride or by the displacement of ring-bound bromine or iodine by trifluoromethylcopper generated in situ. The carboxy function was produced by treatment of organolithium or organomagnesium intermediates, products of halogen/metal or hydrogen/ metal permutation, with carbon dioxide. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
