590372-03-5 Usage
Uses
Used in Pharmaceutical Industry:
8-Bromo-2-chloro-3-(trifluoromethyl)quinoline is used as a building block for the synthesis of new drugs. Its unique structure and properties make it a promising candidate for the development of pharmaceuticals.
Used in Agrochemical Industry:
8-Bromo-2-chloro-3-(trifluoromethyl)quinoline is used as a chemical intermediate in the synthesis of agrochemicals. Its specific chemical properties make it suitable for use in this industry.
Used in Materials Science:
8-Bromo-2-chloro-3-(trifluoromethyl)quinoline is used in the development of new materials. Its unique structure and properties make it a valuable tool for researchers in materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 590372-03-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,0,3,7 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 590372-03:
(8*5)+(7*9)+(6*0)+(5*3)+(4*7)+(3*2)+(2*0)+(1*3)=155
155 % 10 = 5
So 590372-03-5 is a valid CAS Registry Number.
590372-03-5Relevant academic research and scientific papers
Recommendable routes to trifluoromethyl-substituted pyridine- and quinolinecarboxylic acids
Cottet, Fabrice,Marull, Marc,Lefebvre, Olivier,Schlosser, Manfred
, p. 1559 - 1568 (2007/10/03)
As part of a case study, rational strategies for the preparation of all ten 2-, 3-, or 4-pyridinecarboxylic acids and all nine 2-, 3-, 4-, or 8-quinolinecarboxylic acids bearing trifluoromethyl substituents at the 2-, 3-, or 4-position were elaborated. The trifluoromethyl group, if not already present in the precursor, was introduced either by the deoxygenative fluorination of suitable carboxylic acids with sulfur tetrafluoride or by the displacement of ring-bound bromine or iodine by trifluoromethylcopper generated in situ. The carboxy function was produced by treatment of organolithium or organomagnesium intermediates, products of halogen/metal or hydrogen/ metal permutation, with carbon dioxide. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
