59096-18-3

Upstream product

• 70503-69-4 N-methyl-3a-(4-methoxyphenyl)-cis-octahydroindol-6-one 
• 74-88-4 methyl iodide 
• 20036-55-9 3-<3,4-(dimethoxy)phenyl>-2-cyclohexen-1-ol 
• 20065-80-9 2-(3',4'-dimethoxy-1,2,3,4-tetrahydro-[1,1'-biphenyl]-1-yl)-N,N-imethylacetamide 
• 20036-53-7 3-<3,4-(dimethoxy)phenyl>-2-cyclohexen-1-one 
• 89980-69-8 3,4-dimethoxyphenylmagnesium bromide 
• 126325-74-4 2S-4-(3,4-dimethoxyphenyl)-2-hydroxy-3-cyclohexene-1-one (2S,3S)-1,4-dimethoxy-2,3-butylene acetal 
• 126325-68-6 4-(3,4-dimethoxyphenyl)-3-cyclohexene-1,2-dione 1-<(2S,3S)-1,4-dimethoxy-2,3-butylene>acetal 
• 126325-73-3 2,4-dihydroxy-4-(3,4-dimethoxyphenyl)cyclohexanone 1-(2S,3S)-1,4-dimethoxy-2,3-butylene acetal 
• 126325-69-7 2,4-dihydroxycyclohexanone dimethylacetal 
• 69125-55-9 4-hydroxy-1-methoxy-1-cyclohexene 
• 126325-75-5 4S-4-(3,4-dimethoxyphenyl)-4-(2-N,N-dimethylamino-2-oxo-ethyl)-2-cyclohexene-1-one (2S,3S)-1,4-dimethoxy-2,3-butylene acetal 
• 126325-71-1 2-hydroxy-1,4-cyclohexanedione 1-<(2S,3S)-1,4-dimethoxy-2,3-butylene>acetal 
• 126325-70-0 2,4-dihydroxycyclohexanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal 

Downstream Products

• 82545-14-0 {2-[(1R,4R)-1-(3,4-Dimethoxy-phenyl)-4-methoxy-cyclohex-2-enyl]-ethyl}-dimethyl-amine 
• 59096-21-8 3'-methoxy-4'-O-methyljoubertiaminol 
• 59096-21-8 (1S,4R)-4-(3,4-Dimethoxy-phenyl)-4-(2-dimethylamino-ethyl)-cyclohex-2-enol 

Relevant academic research and scientific papers

Concise Total Syntheses of (±)-Joubertiamine, (±)- O -Methyljoubertiamine, (±)-3′-Methoxy-4′- O -methyljoubertiamine, (±)-Mesembrane, and (±)-Crinane

A method to access cis-3a-aryloctahydroindole alkaloids has been developed through a key strategy involving Eschenmoser-Claisen rearrangement of allylalcohol. This approach gives us an opportunity to access the all-carbon quaternary center required for ci

Oxidative Friedel-Crafts reaction and its application to the total syntheses of Amaryllidaceae alkaloids

An oxidative Friedel-Crafts reaction involving different aromatic compounds mediated by a hypervalent iodine reagent has been performed, using polysubstituted phenols. The strategy fits within the concept of "aromatic ring umpolung", which opens up novel

Asymmetric Synthesis Using Chiral Acetals: Highly Stereoselective Reduction of Chiral α-Keto-β,γ-unsaturated Acetals and Its Application for the Synthesis of (R)-(-)- and (S)-(+)-3'-Methoxy-4'-O-methyljoubertiamine

Reduction of the chiral α-keto-β,γ-unsaturated acetals (1) derived from (-)-(2S,3S)-1,4-dimethoxy-2,3-butanediol was studied.Extremily high stereoselectivity was attained with LiAlH4 and two epimeric allyl alcohols (2aA-2cA and 2aB-2cB) were prepared selectively by a proper choice of additive.As an application of this methodology, total syntheses of (R)-(-)-3'-methoxy-4'-O-methyljoubertiamine and its enantiomer were achieved from the single chiral enone acetal (3) through a highly stereocontrolled reduction followed by the Claisen-Eschenmoser rearrangement.