5911-65-9

Basic information

• Product Name: 9,10-DIMETHOXY-1,6,7,11B-TETRAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE-2,4(3H)-DIONE
• Synonyms: 9,10-DIMETHOXY-1,6,7,11B-TETRAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE-2,4(3H)-DIONE;9,10-dimethoxy-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinoline-2,4-dione
• CAS NO: 5911-65-9
• Molecular Formula: C15H17NO4
• Molecular Weight: 275.3
• Mol File: 5911-65-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 9,10-DIMETHOXY-1,6,7,11B-TETRAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE-2,4(3H)-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 9,10-DIMETHOXY-1,6,7,11B-TETRAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE-2,4(3H)-DIONE(5911-65-9)
• EPA Substance Registry System: 9,10-DIMETHOXY-1,6,7,11B-TETRAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE-2,4(3H)-DIONE(5911-65-9)

Safety Data

• Hazardous Substances Data: 5911-65-9(Hazardous Substances Data)

Upstream product

• 779276-44-7 C₁₆H₂₁NO₅ 
• 3382-18-1 6,7-dimethoxy-3,4-dihydro-isoquinoline 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 81701-46-4 (E)-4-(2-Benzyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-3-methoxy-but-2-enoic acid methyl ester 
• 5096-82-2 benzyl-6,7-dimethoxy-3,4-dihydroisoquinolin-2-ium hydrobromide 
• 81701-54-4 2,9,10-Trimethoxy-1,6,7,11b-tetrahydro-pyrido[2,1-a]isoquinolin-4-one 

Relevant articles and documents

GLUCOSE METABOLISM MODULATING COMPOUNDS

The present invention provides, inter alia, dihydropyridone compounds and compositions, including analogs of a vesicular monoamine transporter type 2 (VMAT2) antagonist. The present invention also provides methods of using such compounds/analogs for modulating glucose levels, and/or preventing, treating, or ameliorating the effects of diabetes and hyperglycemia.

Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists

Vesicular monoamine transporter type 2 (VMAT2) is a newly emerging target for both diagnostic and therapeutic applications in diabetes mellitus. In pursuit of novel VMAT2 antagonists, we identified a potent hypoglycemic agent with a novel dihydropyridone

A NEW SYNTHETIC METHOD OF NITROGEN HETEROCYCLES THROUGH A NOVEL ANNULATION

A new zinc promoted coupling reaction of iminium salts with alkyl halides gave a variety of nitrogen heterocycles through a novel annulation process.