59115-51-4

Basic information

• Product Name: 7-tolyl-2-methoxynaphthalene
• Synonyms: 7-tolyl-2-methoxynaphthalene
• CAS NO: 59115-51-4
• Molecular Weight: 248.324
• Mol File: 59115-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-tolyl-2-methoxynaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 7-tolyl-2-methoxynaphthalene(59115-51-4)
• EPA Substance Registry System: 7-tolyl-2-methoxynaphthalene(59115-51-4)

Safety Data

• Hazardous Substances Data: 59115-51-4(Hazardous Substances Data)

Upstream product

• 200875-36-1 2-bromo-7-methoxy-naphthalene 
• 5720-05-8 4-methylphenylboronic acid 

Downstream Products

• 1012085-52-7 2,7-di(p-tolyl)naphthalene 

Relevant articles and documents

Nickel Carbodicarbene Catalyzes Kumada Cross-Coupling of Aryl Ethers with Grignard Reagents through C–O Bond Activation

The development of a cross-coupling reaction protocol between aryl ethers and Grignard reagents catalyzed by carbodicarbene (CDC) nickel complexes to afford biaryl compounds through C–O cleavage is reported. Aromatic substrates featuring a broad range of electron neutral, donating, or withdrawing groups are introduced at the desired position. The method has proven effective over a wide range of naphthyl methyl ethers, anisoles, and Grignard reagents. The robustness of the protocol is validated by performing multiple cleavage reactions, gram scale synthesis, and arylation of a dimethoxy esterdiol derivative.