591212-29-2Relevant academic research and scientific papers
Some transformations of 2-amino-4-phenyl-1,3-thiazole
Sadigova,Magerramov,Allakhverdiev,Vekilova
, p. 787 - 789 (2004)
Reactions of 2-amino-4-phenyl-1,3-thiazole with aromatic aldehydes, phenyl isocyanate, and carboxylic acid chlorides were studied.
Structure-activity relationship study of E6 as a novel necroptosis inducer
Mou, Jianfeng,Park, Ann,Cai, Yu,Yuan, Junying,Yuan, Chengye
, p. 3057 - 3061 (2015/06/22)
Necroptosis inducers represent a promising potential treatment for drug-resistant cancer. We herein describe the structure modification of E6, which was identified recently as a potent and selective necroptosis inducer. The studies described herein demonstrate for the first time that functionalized biphenyl derivatives possess necroptosis inducer activity. Furthermore, these studies have led to the identification of two promising compounds (5h and 5j) that can be used for further optimization studies as well as mechanism of action investigations.
Synthesis and antioxidant activity of 2-amino-4-phenyl-1,3-thiazole derivatives
Rzaeva,Sadigova,Vekilova,Farzaliev,Magerramov,Allakhverdiev
, p. 436 - 440 (2007/10/03)
Azomethines and their hydrogenated derivatives were synthesized in the reaction of 2-amino-4-phenyl-1,3-thiazole with various hydroxyl-containing aldehydes. The synthesized compounds exhibit high antioxidant activity in the inhibited oxidation of cumene.
