59128-02-8

Usage

Uses

Used in Pharmaceutical Industry:
Imidazo[1,2-a]pyridine-2-acetic acid, 6-chloro-, ethyl ester is used as a building block for the synthesis of potential drug candidates. Its unique chemical structure and chloro substitution may contribute to the development of new therapeutic agents with novel mechanisms of action.
Used in Agrochemical Industry:
In the agrochemical industry, Imidazo[1,2-a]pyridine-2-acetic acid, 6-chloro-, ethyl ester is also used as a building block for the synthesis of agrochemicals. Its specific applications may include the development of new pesticides, herbicides, or other agricultural chemicals that can improve crop yield and protect against pests.

InChI:InChI=1/C11H11ClN2O2/c1-2-16-11(15)5-9-7-14-6-8(12)3-4-10(14)13-9/h3-4,6-7H,2,5H2,1H3

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 84911-18-2 ethyl 2-bromoacetoacetate 
• 638-07-3 ethyl (2-chloroaceto)acetate 

Downstream Products

• 59128-13-1 2-(6-chloroimidazo[1,2-a]pyridin-2-yl)acetic acid 

Relevant academic research and scientific papers

Compounds for treating spinal muscular atrophy

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. In a specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN2 into mRNA that is transcribed from the SMN2 gene. In another specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 into mRNA that is transcribed from the SMN1 gene. In yet another embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 and SMN2 into mRNA that is transcribed from the SMN1 and SMN2 genes, respectively.

FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY

A series of substituted fused tricyclic imidazole derivatives, in particular dihydro- 1H-pyrano[4',3':4,5]imidazo[1,2-a]pyridine, 1,2,3,4-tetrahydroimidazo[1,2-a:5,4- c']dipyridine, dihydro-1H-pyrano[3',4':4,5]imidazo[1,2-a]pyridine and tetrahydro-6H- cyc

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. In a specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN2 into mRNA that is transcribed from the SMN2 gene. In another specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 into mRNA that is transcribed from the SMN1 gene. In yet another embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 and SMN2 into mRNA that is transcribed from the SMN1 and SMN2 genes, respectively.

In search of imidazo [1,2-a] pyridine derivatives exhibiting resistance for catalytic hydrogenation

Effect of substituents on the pyridine ring of imidazo [1,2-a] pyridine derivatives have been studied to ascertain the structural requirement for offering resistance towards catalytic hydrogenation of the title compounds.