59137-64-3Relevant academic research and scientific papers
Chromium-Catalyzed Linear-Selective Alkylation of Aldehydes with Alkenes
Hirao, Yuki,Kanai, Motomu,Katayama, Yuri,Mitsunuma, Harunobu
supporting information, (2020/11/18)
We developed a chromium-catalyzed, photochemical, and linear-selective alkylation of aldehydes with alkylzirconium species generated in situ from a wide range of alkenes and Schwartz's reagent. Photochemical homolysis of the C-Zr bond afforded alkyl radicals, which were then trapped by a chromium complex catalyst to generate the alkylchromium(III) species for polar addition to aldehydes. The reaction proceeded with high functional group tolerance at ambient temperature under visible-light irradiation.
Diastereoselective addition of organometallic reagents to chiral iminium ions: Synthesis of (S)-(+)-cryptostyline I
Polniaszek, Richard P.,Dillard, Lawrence W.
, p. 797 - 800 (2007/10/02)
Iminium ion 2c participates in stereoselective nucleophilic addition reactions with Grignard reagents. Analysis of the products from reaction of 5-hexenylmagnesium bromide with iminium ion 2a suggests that these reactions proceed by a polar (two electron) mechanism. The utility of this chemistry is demonstrated in a stereo specific synthesis of (5)-(+)-cryptostylina I.
Preparation of Alkylchromium Reagents by Reduction of Alkyl Halides with Chromium(II) Chloride under Cobalt Catalysis
Takai, Kazuhiko,Nitta, Kenji,Fujimura, Osamu,Utimoto, Kiitiro
, p. 4732 - 4734 (2007/10/02)
Alkyl halides and tosylates are reduced with CrCl2 in the presence of a catalytic amount of vitamin B12 or cobalt phthalocyanine to give alkylchromium reagents, which add to aldehydes without affecting the coexisting ketone or ester groups.
Synthesis and Reaction of 1,2,4-Trioxanes
Fujisaka, Tomohiro,Miura, Masahiro,Nojima, Masatomo,Kusabayashi, Shigekazu
, p. 1031 - 1039 (2007/10/02)
The peroxides (1a-e) and epoxides (2a-g) in methylene dichloride were treated with tungsten (VI) oxide and then with catalitic amounts of chlorosulphonic acid to give the corresponding 1,2,4-trioxanes (3a-r) in 10-63percent yield.The mode of decomposition of the 1,2,4-trioxanes was studied by treating a number with the following reagents: triethylamine, sodium ethoxide, lithium di-isopropylamide, Grignard and lithium reagents, lithium aluminium hydride, anthrylsodium, triphenylphosphine, and titanium tetrachloride.
