59146-33-7Relevant academic research and scientific papers
Discovery and evaluation of pyrazolo[1,5-a]pyrimidines as neuropeptide Y1 receptor antagonists
Griffith, David A.,Hargrove, Diane M.,Maurer, Tristan S.,Blum, Charles A.,De Lombaert, Stéphane,Inthavongsay, John K.,Klade, Lee E.,MacK, Christine M.,Rose, Colin R.,Sanders, Martin J.,Carpino, Philip A.
scheme or table, p. 2641 - 2645 (2011/06/20)
A novel series of pyrazolo[1,5-a]pyrimidine derivatives was synthesized and evaluated as NPY Y1R antagonists. High binding affinity and selectivity were achieved with C3 trisubstituted aryl groups and C7 substituted 2-(tetrahydro-2H-pyran-4-ylamino)ethyla
Fused heterotricyclic compounds, process for preparing the compounds and drugs containing the same
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, (2008/06/13)
The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula, a pharmacologically acceptable salt thereof or hydrat
