59168-56-8

Basic information

• Product Name: Methyl 4-amino-2-methoxy-5-thiocyanobenzoate
• Synonyms: methyl 4-amino-5-thiocyanato-o-anisate;4-AMINO-2-METHOXY-5-THIOCYANATOBENZOIC ACID METHYL ESTER;METHYL4-AMINO-2-METHOXY-5-THIOCYANATOBENZOATE;THIOCYANATOBENZOATE;Methyl 4-amino-2-methoxy-5-thiocyanobenzoate;Einecs 261-639-0;4-AMino-5-(cyanosulfanyl)-2-Methoxybenzoic Acid Methyl Ester
• CAS NO: 59168-56-8
• Molecular Formula: C₁₀H₁₀N₂O₃S
• Molecular Weight: 238.26
• EINECS: 261-639-0
• Product Categories: Aromatics Compounds;Aromatics;Sulfur & Selenium Compounds
• Mol File: 59168-56-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 160-165°C
• Boiling Point: 422 °C at 760 mmHg
• Flash Point: 209 °C
• Appearance: yellow solid
• Density: 1.35 g/cm³
• Vapor Pressure: 2.5E-07mmHg at 25°C
• Refractive Index: 1.603
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: Methyl 4-amino-2-methoxy-5-thiocyanobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-amino-2-methoxy-5-thiocyanobenzoate(59168-56-8)
• EPA Substance Registry System: Methyl 4-amino-2-methoxy-5-thiocyanobenzoate(59168-56-8)

Safety Data

• Hazardous Substances Data: 59168-56-8(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

Uses

Methyl 4-Amino-2-methoxy-5-thiocyanobenzoate is an Amisulpride (A633250) impurity.

InChI:InChI=1/C10H10N2O3S/c1-14-8-4-7(12)9(16-5-11)3-6(8)10(13)15-2/h3-4H,12H2,1-2H3

Upstream product

• 65-49-6 4-Aminosalicylic acid 
• 27492-84-8 Methyl 4-amino-2-methoxybenzoate 
• 1147550-11-5 ammonium thiocyanate 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 1119455-01-4 methyl 4-amino-5-(ethylthio)-2-methoxybenzoate 
• 71675-87-1 2-methoxy-4-amino-5-ethylsulphonyl benzoic acid 
• 71675-85-9 amisulpride 
• 71675-98-4 2-methoxy-4-amino-5-methylthio benzoic acid 

Relevant articles and documents

BENZOTHIADIAZOLAMINES

The present invention relates to substituted benzothiadiazolamine compounds of general formula(I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.

SUBSTITUTED BENZOAZOLE PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS

The invention relates to substituted benzothiazoles, benzoxazoles—and their counterparts having pyridine and pyrimidine rings replacing the benzene ring—that are PDE4 inhibitors useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions, to pharmaceutical compositions comprising these compounds, and to methods for the treatment of stroke, myocardial infarct, and cardiovascular inflammatory conditions in a mammal. The compounds have general formula I: in which A and B are carbocycles or heterocycles. A particular embodiment is