591733-74-3

Basic information

• Product Name: Oxazolidine, 3-(methoxymethyl)-4-methyl-5-phenyl-, (4R,5S)-
• CAS NO: 591733-74-3
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.272
• Mol File: 591733-74-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Oxazolidine, 3-(methoxymethyl)-4-methyl-5-phenyl-, (4R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazolidine, 3-(methoxymethyl)-4-methyl-5-phenyl-, (4R,5S)-(591733-74-3)
• EPA Substance Registry System: Oxazolidine, 3-(methoxymethyl)-4-methyl-5-phenyl-, (4R,5S)-(591733-74-3)

Safety Data

• Hazardous Substances Data: 591733-74-3(Hazardous Substances Data)

Upstream product

• 37577-28-9 (1S,2R)-(+)-norphedrine 
• 67-56-1 methanol 
• 144731-09-9 bis((4R,5S)-4-methyl-5-phenyl-1,3-oxazolidin-3-yl)methane 

Relevant articles and documents

Nucleophilic reactions at optically active bis(4-methyl-5-phenyl-1,3-oxazolidin-3-YL)methane

The reagents RMgCl, RLi, NaOMe and amines (R = Me or t-Bu) with bis(4-methyl-5 -phenyl-1,3-oxazolidin-3-yl)methane (1) attack nucleophilically at its endo- or exocyclic methylenic groups (C-2 or C-6) giving: 3-ethyl-4-methyl-5phenyl-1,3-oxazolidine (3), 3-neopentyl-4-methyl-5-phenyl-1,3-oxazolidine (4), 2-[neopentyl-(4-methyl-5-phenylethan-1,3-oxazolidin-3-ylmethyl) amino]-1phenylpropan-1-ol (6), N-neopentyl norephedrine (7), 3-methoxymethyl-4methyl-5-phenyl-1,3-oxazolidine (8), N-benzyl-(4-methyl-5-phenyl-1,3oxazolidin-3-yl)methane (9), 2-chloropropyl-(4-methyl-5-phenyl-1,3-oxazolidin3-ylmethyl)amine (10), 2-[(benzylamino-methyl)amino]-1-phenylpropan-1-ol (11). A high yield synthesis of 3(H)-4-methyl-5-phenyl-1,3-oxazolidine (5) is also reported.