591735-81-8Relevant articles and documents
Synthesis of metabolites of the prodrug 2, 5-bis(4O-methoxyamidinophenyl)furan
Anbazhagan, Mariappan,Saulter, Janelle Y.,Hall, James E.,Boykin, David W.
, p. 1133 - 1145 (2007/10/03)
The synthesis of three metabolites of the prodrug 2,5-bis (4-O-methoxyamidinophenyl)furan (1), 2-(4-hydroxyamidinophenyl)-5-(4-methoxyamidinophenyl)furan (MI), 2-(4-amidinophenyl)-5-(4-ethoxyamidinophenyl)-furan (M3) and 2-(4-amidinophenyl)-5-(4-hydroxyamidinophenyl)furan (M4), is reported. The key step in each of the syntheses involves the Heck reaction.