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D-Proline, (2S)-7-bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]heptanoyl-O-meth yl-D-tyrosyl-L-isoleucyl-, phenylmethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

591772-49-5

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591772-49-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 591772-49-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,1,7,7 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 591772-49:
(8*5)+(7*9)+(6*1)+(5*7)+(4*7)+(3*2)+(2*4)+(1*9)=195
195 % 10 = 5
So 591772-49-5 is a valid CAS Registry Number.

591772-49-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Boc-L-Ab7-D-Tyr(Me)-L-Ile-D-Pro-OBzl

1.2 Other means of identification

Product number -
Other names (R)-1-{(2S,3S)-2-[(R)-2-((S)-7-Bromo-2-tert-butoxycarbonylamino-heptanoylamino)-3-(4-methoxy-phenyl)-propionylamino]-3-methyl-pentanoyl}-pyrrolidine-2-carboxylic acid benzyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:591772-49-5 SDS

591772-49-5Relevant academic research and scientific papers

Cyclic Tetrapeptides Bearing a Sulfhydryl Group Potently Inhibit Histone Deacetylases

Nishino, Norikazu,Jose, Binoy,Okamura, Shinji,Ebisusaki, Shutoku,Kato, Tamaki,Sumida, Yuko,Yoshida, Minoru

, p. 5079 - 5082 (2003)

(Equation presented) New inhibitors of histone deacetylase (HDAC) containing a sulfhydryl group were designed on the basis of the corresponding hydroxamic acid (CHAP31) and FK228. Their disulfide dimers and hybrids exhibited potent HDAC inhibitory activity in vivo with potential as anticancer prodrugs.

Histone deacetylase inhibitors and process for producing the same

-

Page/Page column 12, (2008/06/13)

Compounds represented by formula (1) have strong inhibitory activity that is selective towards HDAC1 and HDAC4. Therefore, the compounds of the present invention are useful as pharmaceutical agents for treating or preventing diseases caused by HDAC1 and HDAC4.

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