591772-75-7Relevant academic research and scientific papers
Visible-Light-Driven Photocatalytic Initiation of Radical Thiol-Ene Reactions Using Bismuth Oxide
Fadeyi, Olugbeminiyi O.,Mousseau, James J.,Feng, Yiqing,Allais, Christophe,Nuhant, Philippe,Chen, Ming Z.,Pierce, Betsy,Robinson, Ralph
supporting information, p. 5756 - 5759 (2015/12/11)
A nontoxic and inexpensive photocatalytic initiation of anti-Markovnikov hydrothiolation of olefins using visible light is reported. This method is characterized by low catalyst loading, thereby enabling a mild and selective method for radical initiation in thiol-ene reactions between a wide scope of olefins and thiols.
Histone deacetylase inhibitors and process for producing the same
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Page/Page column 14, (2008/06/13)
Compounds represented by formula (1) have strong inhibitory activity that is selective towards HDAC1 and HDAC4. Therefore, the compounds of the present invention are useful as pharmaceutical agents for treating or preventing diseases caused by HDAC1 and HDAC4.
Cyclic Tetrapeptides Bearing a Sulfhydryl Group Potently Inhibit Histone Deacetylases
Nishino, Norikazu,Jose, Binoy,Okamura, Shinji,Ebisusaki, Shutoku,Kato, Tamaki,Sumida, Yuko,Yoshida, Minoru
, p. 5079 - 5082 (2007/10/03)
(Equation presented) New inhibitors of histone deacetylase (HDAC) containing a sulfhydryl group were designed on the basis of the corresponding hydroxamic acid (CHAP31) and FK228. Their disulfide dimers and hybrids exhibited potent HDAC inhibitory activity in vivo with potential as anticancer prodrugs.
