59178-15-3Relevant academic research and scientific papers
Antimalarials. 9. Methylthio and methylsulfonyl substituted 9 phenanthrenemethanols
Markovac,LaMontagne
, p. 978 - 982 (1976)
Nine di and trisubstituted 9 phenanthrenemethanols bearing methylthio and methylsulfonyl substituents in the 2 and/or 6 positions of the phenanthrene nucleus were prepared and screened for antimalarial activity against Plasmodium berghei in mice. Six of the nine compounds were curative at or below 160 mg/kg. The most active structures contained a methylthio substituent in combination with two chlorine atoms.
