59182-69-3

Basic information

• Product Name: [2-(4-Cyclohexyl-phenyl)-1-methyl-ethyl]-(3,3-diphenyl-propyl)-amine
• CAS NO: 59182-69-3
• Molecular Weight: 411.63
• Mol File: 59182-69-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(4-Cyclohexyl-phenyl)-1-methyl-ethyl]-(3,3-diphenyl-propyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(4-Cyclohexyl-phenyl)-1-methyl-ethyl]-(3,3-diphenyl-propyl)-amine(59182-69-3)
• EPA Substance Registry System: [2-(4-Cyclohexyl-phenyl)-1-methyl-ethyl]-(3,3-diphenyl-propyl)-amine(59182-69-3)

Safety Data

• Hazardous Substances Data: 59182-69-3(Hazardous Substances Data)

Upstream product

• 5586-73-2 3-diphenylpropyl amine 
• 59182-66-0 4-Cyclohexylphenylaceton 
• 3531-23-5 3-hydroxy-3,3-diphenylpropanenitrile 
• 35889-00-0 (4-cyclohexyl-phenyl)-acetic acid 
• 3531-24-6 3,3-diphenylacrylonitrile 

Relevant articles and documents

Synthesis and pharmacological study of diphenylalkylamines with cycloaliphatic residues; new coronary vasodilators

The paper describes the synthesis and the pharmacological evaluation of some derivatives of prenylamine, all with a cycloaliphatic ring within or instead of the isopropylamine moiety. Where the alicyclic ring had a bulky substituent in para were more active than prenylamine as coronary vasodilators on isolated guinea pig heart (Langendorff). The most interesting derivative was MG 8926 [N (3,3 diphenylpropyl) α methyl β cyclohexylethylamine], which was more active than prenylamine on Langendorff's heart and in enhancing the pressor response to catecholamines and inhibiting the isoprenaline induced hypotension. Moreover, it had almost the same effects as prenylamine as spasmolytic, local and general anesthetic, on heart rate and arterial pressure and against coronary spasm from pitressin.