5925-85-9

Usage

Uses

Used in Pharmaceutical Industry:
P-FLUOROBENZYLMETHYL SULFIDE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs and improve existing ones.
Used in Agrochemical Industry:
P-FLUOROBENZYLMETHYL SULFIDE is used as an intermediate in the synthesis of agrochemicals, playing a role in the development of pesticides and other agricultural products to enhance crop protection and yield.
Used in Fragrance Industry:
P-FLUOROBENZYLMETHYL SULFIDE is used as a component in the production of fragrances, contributing to the creation of unique scents for various applications such as perfumes, cosmetics, and household products.
Used in Flavor Industry:
P-FLUOROBENZYLMETHYL SULFIDE is used in the development of flavors for the food and beverage industry, enhancing taste profiles and creating novel flavor experiences.
Used in Dye Industry:
P-FLUOROBENZYLMETHYL SULFIDE is utilized in the production of dyes, playing a part in the creation of vibrant colorants for textiles, plastics, and other materials.

Upstream product

• 5969-47-1 methyl fluorobenzenedithiocarboxylate 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 5188-07-8 sodium thiomethoxide 
• 459-46-1 4-Fluorobenzyl bromide 
• 71141-61-2 4-FPhCS₂Na 
• 462-06-6 fluorobenzene 
• 2373-51-5 chloro-methylsulfanyl-methane 

Downstream Products

• 5925-83-7 4-fluorobenzyl methyl sulfone 

Relevant academic research and scientific papers

Synthesis of dibenzo[c,e]oxepin-5(7H)-ones from benzyl thioethers and carboxylic acids: Rhodium-catalyzed double C-H activation controlled by different directing groups

A rhodium(III)-catalyzed cross-coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (C-H, C-S, O-H) and the formation of two bonds (C-C, C-O). The formed structure is the privileged core in natural products and bioactive molecules. This work highlights the power of using two different directing groups to enhance the selectivity of a double C-H activation, the first of such examples in cross-oxidative coupling.

Azetidine derivatives, their preparation and medicaments containing them

The invention concerns compounds of formula (1) wherein: R represents a chain (A) or (B); R1 is methyl or ethyl; R2 is either an optionally substituted aromatic or an optionally substituted heteroaromatic ring; R3 and R4, identical or different, are either an optionally substituted aromatic or an optionally substituted heteroaromatic ring; R′ represents a hydrogen atom or a —CO—alk radical, their optical isomers, their salts, their preparation and medicines containing them.

BIOTRANSFORMATION OF ORGANIC SULFIDES. PART 6. FORMATION OF CHIRAL para-SUBSTITUTED BENZYL METHYL SULFOXIDES BY HELMINTHOSPORIUM SPECIES NRRL 4671

The fungus Helminthosporium species NRRL 4671 has been used for the biotransformation of a series of para-substituted benzyl sulfides with substituent groups consisting of trifluoromethyl, halo, hydroxy, methoxy, acetoxy, nitro, cyano, amino, acetamido, acyl and carboxylic acid units.In all cases, sulfoxide formation occurred in good yoeld and with predominant (S) chirality at the sulfur position.A minor amount of sulfone product was also obtained from the halo- and methoxy-substituted substrates.

Superelectrophilic methylthiomethylation of aromatics with chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) reagent

Effective methylthiomethylation of aromatics was achieved by using chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) as the alkylating agent. Excess aluminum chloride activates the thiocarboxonium ion intermediate by coordinating with sulfur and thus diminishes back donation of 'electron density' into the carbocationic center, rendering it a superelectrophilic methylthiomethylating agent.