592508-24-2Relevant academic research and scientific papers
Enantioselective synthesis of the carbocyclic moiety of (-)-carbovir
Roulland, Emmanuel,Monneret, Claude,Florent, Jean-Claude
, p. 4125 - 4128 (2007/10/03)
Enantioselective construction of the protected carbocycle moiety of the anti-HIV drug carbovir was achieved in 11 steps from (S)-(-)-ethyl lactate. The two key steps are a Claisen [3+3] sigmatropic rearrangement of (3S,4E)-3-(4-methoxy-phenoxymethyl)-hex-
